| 番茄汁对镉中毒小鼠体内抗氧化酶活力的影响 |
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| 引用本文： | 庞雅琴,周敏,庞广福,郑子敏,韦健全. 番茄汁对镉中毒小鼠体内抗氧化酶活力的影响[J]. 现代预防医学, 2011, 38(24): 5103-5105 |
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| 作者姓名： | 庞雅琴 周敏 庞广福 郑子敏 韦健全 |
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| 作者单位： | 广西右江民族医学院预防医学教研室,百色,533000 |
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| 基金项目： | 右江民族医学院院级科研课题(200514) |
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| 摘 要： | [目的]比较番茄汁和单体番茄红素对镉中毒小鼠抗氧化酶活力影响的差异.[方法]小鼠饲喂CdCl2、番茄红素或不同浓度番茄汁,4周后处死,测定肝、肾镉含量,测血清尿素氮(BUN)及谷丙转氨酶(ALT)的含量,测定血、肝、肾超氧化物岐化酶(SOD)活性、丙二醛(MDA)的含量、谷胱甘肽过氧化物酶(GSH-Px)的活力. [结果]与染镉组相比,番茄红素、番茄汁可促进肝、肾镉的排出,降低BUN、ALT的含量,降低血、肝、肾MDA的含量,使SOD、GSH-PX的活力恢复,以上各指标中,番茄汁随着浓度增大作用加强,低剂量组的作用虽比番茄红素组差,中剂量组的作用与番茄红素组相比无差别,高剂量组的作用比番茄红素组强.[结论]番茄汁对镉中毒小鼠肝、肾损伤的保护作用强于番茄红素,这可能与番茄红素和果汁中的其他植物化学物质发挥协同作用有关.
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| 关 键 词： | 番茄汁 番茄红素 镉中毒 抗氧化 |
EFFECT OF TOMATO JUICE ON ANTIOXIDATIVE ENZYME IN MICE INDUCED BY CD |
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| PANG Ya-qin,ZHOU Min,PANG Guang-fu,et al.. EFFECT OF TOMATO JUICE ON ANTIOXIDATIVE ENZYME IN MICE INDUCED BY CD[J]. Modern Preventive Medicine, 2011, 38(24): 5103-5105 |
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| Authors: | PANG Ya-qin ZHOU Min PANG Guang-fu et al. |
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| Affiliation: | PANG Ya-qin,ZHOU Min,PANG Guang-fu,et al.(Department of Preventive Medicine,Youjiang Medical College,Baise 533000,China) |
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| Abstract: | [Objective]To observe the different effects of tomato juice and lycopene on antioxidation in mice induced by Cd.[Methods]The mice were given Cd,lycopene and different concentration of tomato juice. After 4 weeks,the Cd levels of liver and kidney,the activity of alanine aminotranferase(ALT)and the content of blood urea-nitrogen(BUN)in serum of mice were measured. The activitives of superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px),the content of malonydiadehyde(MDA)in serum,liver and kidney of mice... |
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| Keywords: | Tomato juice Lycopene Cadmium Antioxidation |
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