| 紫杉醇联合顺铂化疗方案在晚期食道癌治疗中的临床应用价值分析 |
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| 引用本文： | 王佩.紫杉醇联合顺铂化疗方案在晚期食道癌治疗中的临床应用价值分析[J].现代预防医学,2011,38(24):5139-5140. |
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| 作者姓名： | 王佩 |
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| 作者单位： | 河南省新乡市中心医院肿瘤科,新乡,453000 |
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| 摘 要： | 目的]探讨紫杉醇与顺铂联合化疗方案治疗晚期食道癌(Advanced esophageal cancer)的临床疗效、不良反应及对生活质量的改善程度. 方法] 2007年9月～2010年12月间新乡市中心医院收治并诊断为晚期食道癌患者150例,随机分为观察组和对照组,其中观察组75例,采用紫杉醇与顺铂联合化疗方案；对照组采用顺铂联合氟尿嘧啶方案,评定治疗效果. 结果]按Kamofsky分级标准,观察组评分增高比例为34.7％ (26/75),平均生存时间为(9.8±4.3)个月,均明显优于对照组(P＜0.05).两组反应差异无统计学意义(P＞0.05). 结论]紫杉醇与顺铂联合化疗治疗晚期食道癌疗效显著,可明显改善患者的生活质量.
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| 关 键 词： | 紫杉醇 顺铂 食管癌 |
THE CLINICAL EFFECT OF ANALYSIS OF TAXOL COMBINED WITH CISPLATIN CHEMOTHERAPY IN THE TREATMENT OF ADVANCED ESOPHAGEAL CANCER |
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| WANG Pei.THE CLINICAL EFFECT OF ANALYSIS OF TAXOL COMBINED WITH CISPLATIN CHEMOTHERAPY IN THE TREATMENT OF ADVANCED ESOPHAGEAL CANCER[J].Modern Preventive Medicine,2011,38(24):5139-5140. |
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| Authors: | WANG Pei |
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| Institution: | WANG Pei.(The Department of Oncology,Xinxiang Central Hospital,Xinxiang 453000,China) |
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| Abstract: | Objective]To explore the clinical effect of analysis of taxol combined with cisplatin chemotherapy in the treatment of advanced esophageal cancer.Methods]From September 2007 to December 2010,150 cases of patients with esophageal cancer were were randomly divided into trial group and control group,including observation group 75 cases,using paclitaxel and cisplatin combination chemotherapy regimens;Control group was used by cisplatin plus 5-fluorouracil scheme,and then we evaluated the treatment effect.Res... |
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| Keywords: | Taxol Cisplatin Esophageal cancer |
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