激素释放电极双心腔起搏长期阈值观察

目的：观察激素释放电极对心房和心室起搏阈值长期的影响，检验激素释放电极能否用来长期低能量安全的进行双心腔起搏。方法：８１例患者，男４５例，女３６例，平均年龄６７岁。所有患者应用双心腔频率反应起搏器（ＤＤＤＲ）。心房和心室电极分别采用ＭＥＤＴＲＯＮＩＣ５５２４Ｍ及５０２４Ｍ激素释放电极。心房和心室电极植入后即刻及术后１个月、３个月、６个月、１２个月、１８个月及２４个月分别测试双极心房和心室起搏阈值。结果：心房和心室激素释放电极在随访２４个月期间所有测试的心房和心室起搏阈值保持低水平，呈稳定的平台型，无以往非激素释放电极植入早期的起搏阈值明显升高现象。另外，应用激素释放电极的患者中有９８％的心房起搏阈值及９４％的心室起搏阈值≤１．３Ｖ，因此可安全地以２．５Ｖ的电压进行双心腔起搏。结论：被动固定激素释放电极可保持心房和心室的长期的低起搏阈值状态。使绝大多数应用激素释放电极的患者可长期安全地以２．５Ｖ电压进行双心腔起搏，从而有效地延长双心腔起搏器的使用寿命。

Long Term Performance of Steroid eluting Lead in Dual Chamber Pacing

Objective:A prospective study was undertaken to evaluate both atrial and ventricular bipolar tined steroid eluting leads in long term dual chamber pacing. Methods:Eighty one pairs of leads(Medtronic Capsure SP)were used in 81 patients.Bipolar atrial and ventricular stimulation thresholds were measured immediately and 1,3,6,12,18 and 24 months after implantation of the leads. Results:All leads demonstrated low mean stimulation thresholds during the follow up and more than 94% of leads could be paced chronically in the atrium and ventricle at 2 5 volts. Conclusion:Atrial and ventricular steroid eluting leads have excellent stimulation thresholds allowing low energy and long term dual chamber pacing.