Validation of a German version of the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) |
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| Institution: | 1. Institute of Applied Statistics, Johannes Kepler University, Linz, Austria;2. Department of Neuropsychiatry, St George''s Hospital, London, UK;3. Epilepsy Group, Atkinson Morley Regional Neurosciences Centre, St George''s Hospital, London, UK;4. St George''s University of London, London, UK;5. Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester, UK;6. Department of Psycho-oncology, Leicestershire Partnership NHS Trust, Leicester, UK;7. Department of Neurology, Wagner-Jauregg Neuroscience Centre, Kepler University Hospital, Linz, Austria;1. Behavioral Health Services, Cheyenne Regional Medical Center, Cheyenne, WY, USA;2. Department of Psychiatry, Geisel School of Medicine at Dartmouth College, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH, USA;3. Department of Neurology, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH, USA;4. Leadership Preventive Medicine Residency, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH, USA;1. Neuropharmacology Laboratory, Department of Pharmacology, All India Institute of Medical Sciences, New Delhi 110029, India;2. Department of Neurology, All India Institute of Medical Sciences, New Delhi 110029, India;3. Department of Psychiatry, All India Institute of Medical Sciences, New Delhi 110029, India;4. Translational Health Science and Technology Institute, Faridabad, Haryana, India;1. Service d''explorations fonctionnelles du système nerveux, Clinique du sommeil, CHU de Bordeaux, Place Amélie Raba-Léon, 33076 Bordeaux, France;2. USR CNRS 3413 SANPSY, CHU Pellegrin, Université de Bordeaux, France;3. Aix Marseille Univ, INSERM, INS, Inst Neurosci Syst, Marseille, France;4. Department of Clinical Neurophysiology, Hôpital de la Timone, Assistance Publique-Hôpitaux de Marseille, Marseille, France;5. Department of Neurology, University of Otago, Christchurch, New Zealand;1. Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China;2. Department of Psychiatry, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China;1. Universidade Federal de Sao Paulo (UNIFESP), Department of Psychiatry, Brazil;2. Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), Department of Psychiatry and Medical Psychology, Brazil;3. Universidade Federal de Sao Paulo (UNIFESP), Department of Neurology and Neurosurgery, Brazil |
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| Abstract: | IntroductionGoal of the present study was the validation of a German version of the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E).Methods197 adult epilepsy patients completed the NDDI-E (185 completed both the NDDI-E and BDI). 95 patients received psychiatric consults.Results33 patients received a diagnosis of major depression according to ICD-10 criteria. Internal consistency of the NDDI-E was .83. Receiver operating characteristics (ROC) showed an area under the curve of 0.92. Applying a cutoff score of ≥ 14 resulted in both sensitivity and specificity of 0.85. In the subsample with psychiatric consult, at the same optimal cutoff, sensitivity was 0.92, and specificity was 0.86. Further analyses showed a high concurrent validity with the BDI.DiscussionThe German version of the NDDI-E constitutes a brief and reliable depression screening instrument for epilepsy patients. |
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