荔枝草对小鼠小肠运动研究

目的：采用炭末测定法观察中药荔枝草对小鼠小肠运动的影响。方法：将70只实验小鼠随机分为阳性对照组（枳壳水煎剂组）、荔枝草水煎剂组（10、15、20、25、30g/kg）和生理盐水组,灌胃3d（均为0.2mL/10g）后采用炭末测定法对小鼠的小肠运动情况进行观察分析。结果：荔枝草水煎剂组对小鼠小肠推进率比生理盐水组的推进率明显提高（P〈0.05）;荔枝草水煎剂浓度在10~20g/kg范围内对小肠的推进率逐渐增强,在20~30g/kg范围内其效果逐渐减弱。结论：荔枝草水煎剂有一定的促小肠运动作用,并呈现一定的量效关系,其中以20g/kg浓度的荔枝草水煎剂对小鼠小肠的推动作用最为显著。

Research on Influence of Salvia Plebeian Exerts upon Mice Intestinal Motility

Objective： To study the influence of salvia plebeian exerts upon mice intestinal motility through carbon powder measurement method. Method： 70 mice were randomly divided into positive control group （fructus aurantii decoction groups ）/salvia plebeian decoction group （ 10 g/kg, 15 g/kg,20 g/kg,25 g/kg, 30 g/kg ）and saline group （ respectively 0.2 mL/ 10 g ）, and after 3 days carbon powder measurement method was adopted to observe and analyze mice intestinal motility. Results ： With regards to the impact upon intestinal motility, insalvia plebeian decoction group was more obvious than saline group （P〈0.05）; within the concentration range of 10-20 g/kg, insalvia plebeian decoction gradually increased intestinal motility, while within 20-30 g/kg the effect weakened slowly. Conclusion ： Insalvia plebeian decoction exerts impact on intestinal motility, which shows a certain dose-effect relationship, among which insalvia plebeian decoction with concentration rate of 20 g/kg has the most significant influence upon mice intestinal motility.