The CAP cancer protocols – a case study of caCORE based data standards implementation to integrate with the Cancer Biomedical Informatics Grid |
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| Authors: | Jonathan Tobias Ram Chilukuri George A Komatsoulis Sambit Mohanty Nicholas Sioutos Denise B Warzel Lawrence W Wright Rebecca S Crowley |
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| Affiliation: | (1) Department of Pathology, University of California at Los Angeles School of Medicine, Los Angeles, CA, USA;(2) SemanticBits, LLC, Reston, VA, USA;(3) National Cancer Institute Center for Bioinformatics, National Institutes of Health, United States Department of Health and Human Services, Rockville, MD, USA;(4) Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA;(5) Lockheed Martin Information Technology, Rockville, MD, USA;(6) Office of Communications, National Cancer Institute, Rockville, MD, USA;(7) University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA;(8) Center for Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA |
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| Abstract: | Background The Cancer Biomedical Informatics Grid (caBIG™) is a network of individuals and institutions, creating a world wide web of cancer research. An important aspect of this informatics effort is the development of consistent practices for data standards development, using a multi-tier approach that facilitates semantic interoperability of systems. The semantic tiers include (1) information models, (2) common data elements, and (3) controlled terminologies and ontologies. The College of American Pathologists (CAP) cancer protocols and checklists are an important reporting standard in pathology, for which no complete electronic data standard is currently available. |
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