结直肠癌根治术后长期随访结果分析

我院1964年4月～1976年12月根治性切除结直肠癌363例,且随访满10年以上,随访率为97.2％。本组包括结肠癌140例,直肠癌223例。根据Dukes分期法,A期1.7％,B期63.1％,C期35.2％。全部病例均施行根治性切除术,手术死亡率为0.8％(3例)。根治术后5年,10年,15年和20年生存率分别为61.5％,51.9％,48.6％和38.9％。本文对363例结直肠癌进行了临床分析,并将术后生存10年以上的180例和10年内死亡的183例进行比较,以求发现影响术后长期生存的关键因素。结果表明患者年龄、癌瘤部位、病期和淋巴结转移是影响远期疗效最重要的因素。此外,作者通过对治疗失败的原因分析,提出几点提高疗效的措施。

Long-term Follow-up Result of Radical Resection in Patients with Colorectal Cancer

From April 1964 to December 1976,363 patients with colorectal cancer underwent radical resection and followed up for more than 10 years in 97.2%.of the cases of this series 140 cases were colon cancer and 223 rectum.According to Dukes's classification,1.7% was of Stage A,63.1% Stage B,and 35.2% Stage C.All cases underwent radical resection with an operative mortality rate of 0.8% (3 cases).The 5-,10-,15- and 20-year surival rates after curative resection were 61.5%,51.9%,48.6% and38.9% respectively. In this paper the clinical analysis of 363 patients with colorectal cancer was made.Comparing 180 cases alive for more than 10 years with 183 cases dead within 10 years after radical resection,it is shown that the age of the patients,site of tumor,clinical stage and lymph nodes involvement were the most important factors influencing long-term results of radical resection. In addition,the authors,analysed the causes of treatment failure and suggestedeffective measures to improve surgical results.