| 普罗布考对急性冠状动脉综合征患者血清髓过氧化酶和高敏C反应蛋白的影响 |
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| 引用本文： | 王立真. 普罗布考对急性冠状动脉综合征患者血清髓过氧化酶和高敏C反应蛋白的影响[J]. 泰山医学院学报, 2010, 31(2): 103-105 |
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| 作者姓名： | 王立真 |
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| 作者单位： | 泰山医学院附属泰山医院心内科,山东,泰安,271000 |
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| 摘 要： | 目的探讨普罗布考对急性冠状动脉综合征患者血清髓过氧化酶及高敏C反应蛋白的影响及其可能机制。方法将急性冠状动脉综合征患者随机分为普罗布考组和对照组，分别检测治疗前后血清髓过氧化酶和高敏C反应蛋白的浓度。结果普罗布考组和对照组血清髓过氧化酶和高敏C反应蛋白浓度均明显下降（P〈0．001）；但普罗布考组较对照组血清髓过氧化酶下降更加明显（P〈0．05）。结论普罗布考能降低急性冠状动脉综合征患者血清髓过氧化酶和高敏C反应蛋白水平，普罗布考更有效地降低急性冠状动脉综合征患者血清髓过氧化酶，其可能部分解释普罗布考的抗炎和抗氧化作用。
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| 关 键 词： | 普罗布考 急性冠状动脉综合征 髓过氧化酶 C反应蛋白 |
The effects of probucol on serum myeloperoxidase and high sensitive C-reactive protein concentrations in patients with acute coronary syndrome |
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| WANG Li-Zhen. The effects of probucol on serum myeloperoxidase and high sensitive C-reactive protein concentrations in patients with acute coronary syndrome[J]. Journal of Taishan Medical College, 2010, 31(2): 103-105 |
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| Authors: | WANG Li-Zhen |
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| Affiliation: | WANG Li-Zhen(Dept.of Cardiology,Taian City Central Hospital,Taian 271000,China) |
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| Abstract: | Objective: To investigate the effects of Probucol on serum myeloperoxidase(MPO) and high sensitive C-reactive protein(hs-CRP) concentrations in patients with acute coronary syndrome(ACS). Methods: 154 patients with ACS were randomly separated into Probucol treatment group and control group.The serum concentration of MPO and hs-CRP was measured before and after treatment. Results: Serum MPO and hs-CRP concentrations were significantly lower after treatment in the two groups(P<0.001).Compared with control gro... |
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| Keywords: | probucol acute coronary syndrome myeloperoxidase C-reactive protein |
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