内镜下注射止血与金属钛夹止血治疗急性非静脉曲张性上消化道出血疗效比较

目的：比较内镜下注射止血与金属钛夹止血治疗急性非静脉曲张性上消化道出血的临床疗效。方法选择东莞市石排医院2015年1~10月收治的88例急性非静脉曲张性上消化道出血患者，根据随机数表法随机分为观察组与对照组，每组44例。对照组采用内镜下药物注射止血，观察组采用内镜下金属钛夹止血，比较两组患者的止血及并发症发生情况。结果两组患者均未发生穿孔、幽门梗阻、败血症等严重并发症；观察组患者即时止血率和有效止血率分别为100.00%(44/44)和97.73%(43/44)，均明显高于对照组的90.91%(40/44)和84.09%(37/44)，差异均有统计学意义(P<0.05)；观察组患者72 h后再出血发生率为2.27%(1/44)，外科手术率为0(0/44)，均明显低于对照组的13.64%(6/44)和9.09%(4/44)，差异均有统计学意义(P<0.05)。结论内镜下金属钛夹止血治疗急性非静脉曲张性上消化道出血的疗效优于注射止血，且能降低患者的再出血率及外科手术率。

Comparison of therapeutic effect of endoscopic injection hemostasis and metallic titanium clip hemostasis in the ;treatment of acute non-varicose upper gastrointestinal bleeding

Objective To compare the clinical efficacy of endoscopic injection hemostasis and metallic tita-nium clip hemostasis in the treatment of acute non-varicose upper gastrointestinal bleeding. Methods Eighty-eight patients with acute non-varicose upper gastrointestinal bleeding treated in Dongguan Shipai Hospital from January 2015 to October 2015 were selected, which were randomly divided into observation group and control group according to the random number table, with 44 patients in each group. The control group was treated with endoscopic injection he-mostasis, and the observation group were treated with endoscopic hemoclip hemostasis. The bleeding and complica-tions of patients were compared in the two groups. Results In the two groups, there were no serious complications such as perforation, pyloric obstruction, sepsis. The rates of the immediate hemostasis and the effective hemostasis were 100.00% (44/44), 97.73% (43/44) in the observation group, which were significantly higher than those in the control group 90.91%(40/44), 84.09%(37/44)], with statistically significant differences (P<0.05). The incidence of 72 h hemorrhage and surgical operation rate in the observation group were significantly lower than those in the con-trol group 2.27% (1/44) vs 13.64% (6/44), 0 (40/44) vs 9.09% (4/44)], with statistically significant differences (P<0.05). Conclusion Endoscopic metal titanium clip hemostasis in the treatment of acute non-varicose upper gastroin-testinal bleeding is superior to injection hemostasis, and can reduce the rate of bleeding and surgical operation.