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HPLC法测定木瓜丸中阿魏酸的含量
引用本文:赵排风,刘卫超. HPLC法测定木瓜丸中阿魏酸的含量[J]. 中国药事, 2009, 23(10): 1003-1004
作者姓名:赵排风  刘卫超
作者单位:1. 河南省灵宝市食品药品检验所,灵宝,472500
2. 灵宝市卫生防疫站
摘    要:目的HPLC法测定木瓜丸中阿魏酸的含量。方法采用Sino Chrom ODS-BP色谱柱;流动相为甲醇-0.1%磷酸(40∶60),检测波长为320nm。结果阿魏酸在0.1~0.6μg范围内进样量与峰面积呈现良好的线性关系(r=0.9994,n=5);平均回收率为95.8%(RSD=1.3%,n=6)。结论该方法简便、准确,重现性好,可用于木瓜丸中阿魏酸含量的测定。

关 键 词:HPLC  阿魏酸  木瓜丸  含量

Determination of Ferulic Acid in Mugua Pills by HPLC
Zhao Paifeng,Liu Weichao. Determination of Ferulic Acid in Mugua Pills by HPLC[J]. Chinese Pharmaceutical Affairs, 2009, 23(10): 1003-1004
Authors:Zhao Paifeng  Liu Weichao
Affiliation:Zhao Paifeng and Liu Weichao (Institute for Food and Drug Control of Lingbao City, Lingbao 472500; 1The Health and Epidemic Prevention Station of Lingbao)
Abstract:Objective A method for determination of ferulic acid in Mugua Pills by HPLC.Methods Sino Chrom ODS-BP Column was used with methanol-0.1% phosphoric acid(40∶60)as mobile phase and UV detection wavelength was at 320nm.Results There was a good linearity between the concentration of ferulic acid and absorption area value in range of 0.1-0.6μg(r=0.9994,n=5).The average recovery rate was 95.8%(RSD=1.3%,n=6).Conclusions The method is simple and accurate.It can be used for determination of ferulic acid in Mugua Pills.
Keywords:HPLC
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