复方灌肠液治疗溃疡性结肠炎的临床观察

目的观察西医内科基础治疗辅以复方灌肠液保留灌肠治疗溃疡性结肠炎的临床疗效。方法将80例患者随机分为治疗组及对照组各40例，对照组口服柳氮磺胺毗啶（SASP）1．0g，4次／d；治疗组在此基础上加用复方灌肠液保留灌肠，14d为1疗程，连用3个疗程。比较两组患者治疗前后的临床症状、疾病活动指数（DAI）、肠镜表现、复发情况及不良反应。结果治疗组患者的临床症状、DAI、肠镜表现明显改善，复发率低，对照组改善不明显，差异有统计学意义（P〈0．05），两组不良反应发生率差异无统计学意义（P〉0．05）。结论SASP口服联合复方灌肠液保留灌肠治疗溃疡性结肠炎，疗效显著，简便实用，值得临床推广。

The clinical observation of compound recipe enema in the Treatment of ulcerative colitis

Objective To observed the clinical effect of compound recipe enema in the treatment of ulcerative colitis based on western medical treatment.Methods 80patients were randomly divided into control group(n = 40)and therapy group (n = 40).The group was treated with sulfasalazine (SASP),1.0 g,qid; the treatment group were added based on compound recipe enema retention enema,14 d for a course of treatment,three courses used in conjunction.Compared with clinical symptoms,disease activity index (DAI),colonoscopy performance,relapse,and adverse reactions before and after treatment in two groups.Results The clinical symptoms,DAI,colonoscopy performance and relapse were significant difference (P＜0.05) ,the incidence of adverse reactions was no significant difference (P＞0.05).Conclusion SASP combine with compound enema recipe retention enema to treat ulcerative colitis,a significant curative effect 、simple and practical,It deserves to be popularized.