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SCC在鼻咽癌患者血清中表达的临床意义
引用本文:陈传本,潘建基,邱素芳,陈燕. SCC在鼻咽癌患者血清中表达的临床意义[J]. 实用肿瘤学杂志, 2006, 20(5): 384-385
作者姓名:陈传本  潘建基  邱素芳  陈燕
作者单位:福建医科大学教学医院福建省肿瘤医院,福州,350014
摘    要:
目的 探讨鼻咽癌患者血清中鳞状细胞癌抗原(SCC)的表达及临床意义.方法 用酶联免疫吸附法分析186例鼻咽癌患者检测血清SCC水平,并结合临床资料分析该指标的临床意义.结果 鼻咽癌患者SCC阳性率治疗前为29.03%,临床分期之间阳性率差别有统计学意义(P<0.05),治疗后阳性率均表现下降,总的阳性率为7.0%.结论 SCC作为早诊手段,其敏感性较低,但在初诊鼻咽癌中的阳性率随病期增高,对病情预后监测有临床意义.

关 键 词:鳞状细胞癌抗原(SCC)  鼻咽癌  表达  
收稿时间:2006-06-23
修稿时间:2006-06-23

Expression of squamous cell carcinoma antigen and its clinical significance in the patients with nasopharyngeal carcinoma
CHEN Chuanben,PAN Jianji,QIU Sufang,CHEN Yan. Expression of squamous cell carcinoma antigen and its clinical significance in the patients with nasopharyngeal carcinoma[J]. Journal of Practical Oncology, 2006, 20(5): 384-385
Authors:CHEN Chuanben  PAN Jianji  QIU Sufang  CHEN Yan
Affiliation:Fujian Provincial Tumor Hospital, Teaching Hospital of Fujian Medical University, Fuzhou 350014
Abstract:
Objective To investigate the expression of squamous cell carcinoma antigen and its clinical significance in the patients with nasopharyngeal carcinoma.Methods Serum of 186 patients with nasopharyngeal carcinoma was detected by ELISA, the clinical characters and the clinical signicance of SCC were analyzed. Results The positive ratio of SCC in primary nasopharyngeal carcinoma patients is 29.03 %, after therapy, the total ratio of SCC is 7.0 %. Conclusion The sensitivity of early diagnosis with SCC in nasopharyngeal carcinoma is not high, but the later patient's clinical stage, the higher the concent of SCC. SCC has clinic significance in prognosis of nasopharyngeal carcinoma.
Keywords:Squamous cell carcinoma antigen (SCC)  Nasopharyngeal carcinoma  Expression
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