Hepatectomy in patients with nonuremic minimal renal failure |
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Authors: | Tokihiko Sawada MD PhD Funji Kita MD PhD Kyu Rokkaku MD PhD Masato Kato MD Mitsugi Shimoda MD PhD Keiichi Kubota MD PhD |
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Institution: | (1) Second Department of Surgery, Dokkyo University School of Medicine, Kitakobayashi 880, Mibu, 321-0293 Tochigi, Japan |
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Abstract: | In this study, the perioperative management and short-term outcome of hepatectomy were evaluated in patients with nonuremic
minimal renal failure to assess the safety of hepatectomy in such patients. Ninety-one patients who underwent hepatectomy
were retrospectively divided into two groups based on their creatinine clearance (Ccr) values: a group with Ccr values ⩾50
but <100 ml/min (group 1; n=77) and a group with Ccr values of ⩾20 to <50 ml/min (group 2; n=14). Preoperative patient characteristics,
intraoperative parameters (including operation time and blood loss), and postoperative management and complications were evaluated.
The preoperative evaluation showed no differences in liver function between the two groups, and there were no statistically
significant differences between the two groups in intraoperative blood loss (522 ml in group 1 and 806 ml in group 2) or intraoperative
urine volume (1.01 ml/kg per hour in group 1 and 0.75 ml/kg per hour in group 2). The difference between the two groups in
postoperative complications was not statistically significant. None of the patients in group 2 required dialysis therapy,
and no patients died as a result of hepatectomy or hepatectomy-related causes. Adequate indications, appropriate operative
procedures, and perioperative management can enable hepatectomy to be performed safely in patients with nonuremic minimal
renal failure. |
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Keywords: | Hepatectomy nonuremic renal failure hepatocellular carcinoma |
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