193例增厚结节状鲜红斑痣临床分析

目的:通过分析鲜红斑痣增厚结节与年龄、性别的关系,了解鲜红斑痣增厚结节形成的过程,为临床治疗提供参考.方法:对193例确诊为鲜红斑痣的患者,按其临床表现分为无增厚结节组、增厚组、增厚结节组3组.按年龄分为0～19岁和≥20岁2段,然后对与增厚结节形成相关的年龄、性别等因素进行统计学分析.采用SAS6.12软件包.分别对数据进行Fisher确切概率计算和Kruskal-Wallis检验.结果:无增厚结节组165例,占85.49%,增厚组10例,占5.18%;增厚结节组18例、占9.33%.3组之间的年龄分布有统计学差异(P<0.01).0～19岁段94例,≥20岁段99例,增厚结节鲜红斑痣的分布有年龄差异(P<0.01),但无性别差异(P>0.01).结论:随年龄增加,部分鲜红斑痣患者形成增厚、结节病灶,且发生年龄有差异.

Clinical analysis of 193 patients with thickening and nodular port wine stains

PURPOSE: The purpose of this study is to investigate the relation between age, gender and thickening and nodules in port wine stains(PWS) patients. METHODS: The gender and age of 193 cases with port wine stains were compared between those with flat, those with thickening, those with thickening and nodules, in 0-19, 20-year age group. SAS6012 software package was used for Fisher's exact test and Kruskal-Wallis test. RESULTS: There were 165 cases with flat (85.49%), 10 cases with thickening (5.18%), 18 cases with thickening and nodules (9.33%). Kruskal-Wallis test demonstrated significant difference between 2 age groups(P<0.01).There was an increase incidence of thickening, and thickening and nodule formation in 0-19, 20-year age group(P<0.01), but there was no gender difference between thickening and nodules.The data were analyzed by SAS6.12 Fisher's exact test and Kruskal-Wallis test. CONCLUSION: The incidence of thickening and nodule formation in PWS increase with age.