高血压左室肥厚QT间期离散度与室性心律失常及心率变异性之间关系的探讨

目的 探讨高血压左室肥厚（ＬＶＨ）和非左室肥大（ＮＬＶＨ）ＱＴ间期离散度（ＱＴｃｄ）与室性心律失常及心率变异性（ＨＲＶ）之间的关系。关系 对８６例高血压患者分为有或无左室肥厚两组进行ＱＴｃｄ与２４ｈ动态心电图及ＨＲＶ测定。结果 发现高血压ＬＶＨ组的ＱＴｃｄ延长和室性心律失常明显高于高血压ＮＬＶＨ组（Ｐ〈０．０１），而高血压ＬＨＶ组的ＨＲＶ明显低于高血压ＮＬＶＨ组（Ｐ〈０．０１）。结论 高血压ＬＶＨ

The study on relationship between QT interval dispersion,ventricular arrhythmia and heart rate variability in hypertension with left ventricular hypertrophy

Objective To investigate the relationship between QT interval dispersion(QTcd),ventricular arrhythmia and heart rate variability(HRV)in hypertension patients with or without left ventricular hypertrophy(LVH or NLVH). Methods The QTd,corrected QTd(QTcd)and circadian ambulatory ECG and HRV in 86 hypertension parients with LVH or NLVH were measured. Results The prolongation of QTcd and ventricular arrhythmia in hypertension LVH group were significantly higher than that in hypertension NLVH group ( P <0.01),whereas HRV in hypertension LVH group was decreased more significantly than that in hypertension NLVH group( P <0.01). Conclusion The cause of occurrence of complications such as ventricular arrhythmia was related to the prolongation of QTcd and decreasing of HRV in hypertension with LVH.