探讨超前镇痛在吸脂术中的临床意义

目的探讨泰勒宁在吸脂患者的超前镇痛作用的临床意义。方法40例吸脂手术的受术者,随机分为实验组和对照组,分别在术前口服泰勒宁或葡萄糖酸钙,局麻下行负压吸脂术,采用视觉模拟评分法(visual analogue scale,VAS)观测手术开始、结束时受术者的疼痛程度并记录分析,手术结束后统计受术者对镇痛效果的总体满意度。结果手术开始和结束时实验组(泰勒宁组)VAS评分均低于对照组(葡萄糖酸钙组),P<0.05;两组的不良反应发生率差异无统计学意义(P>0.05)。结论术前口服泰勒宁明显减轻术中、术后疼痛,具有良好的超前镇痛效果。泰勒宁用于吸脂受术者时,能其明显减轻手术疼痛和恐惧感,提高其对手术效果的满意度。

Clinical study of preoperative analgesia for liposuction

Objective To observe the effect of the preoperative analgesia with Oxycodone/Acetaminophen for liposuction. Methods In the double-blind, placebo-controlled clinical trial, 40 patients undergoing the liposuction were randomly assigned into two groups which were received a single oral dose of Oxycodone/Acetaminophen or calcium gluconate respectively before the operation. The degrees of pain were evaluated by visual analogue scale(VAS) at the beginning and the end of the operation. Adverse effects and the overall satisfaction on analgesic therapy were assessed when operation finished. Results The VAS scores of the experimental group were significantly lower than the control group at the beginning and the end of operation (P<0.05). There were no significant differences between the two groups in side effects (P>0.05). Conclusions Oxycodone/Acetaminophen could produce preemptive effect. Preoperative oral administration of Oxycodone/Acetaminophen may provide patients with good analgesia in plastic and cosmetic operation.