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Pupil-sparing third nerve palsies and hemiataxia: Claude’s and reverse Claude’s syndrome
Institution:1. Department of Neurology, University of North Carolina School of Medicine, 170 Manning Drive Campus Box 7025, Chapel Hill, NC 27599-7025, USA;2. Department of Neurology, Vanderbilt University Medical Center, Nashville, TN 37232-8552, USA;1. Department of Interventional Neuroradiology, Rothschild Foundation Hospital, 25 Rue Manin, 75019 Paris, France;2. Department of Neurosurgery, Rothschild Foundation Hospital, Paris, France;1. Department of Neurosurgery, University of Texas Health Science Center, 7703 Floyd Curl Drive, MC 7843, San Antonio, TX 78229, USA;2. School of Medicine, University of Texas Health Science Center, San Antonio, TX, USA;1. Department of Neurology, Haeundae Paik Hospital, Inje University, Busan, Republic of Korea;2. Department of Surgery, Haeundae Paik Hospital, Inje University, Busan, Republic of Korea;1. Department of Neurosurgery, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing 100853, China;2. Department of Neurosurgery, Air Force General Hospital of the Chinese PLA, Haidian District, Beijing, China;3. Department of Anesthesiology, Beijing Military General Hospital, Beijing, China;2. Keck School of Medicine of USC, Los Angeles, Calif
Abstract:We report two patients with midbrain infarction with pupil-sparing third nerve palsies and hemiataxia: one with contralateral ataxia (Claude’s syndrome) and one with ipsilateral ataxia (which we refer to as reverse Claude’s syndrome). We highlight the importance of a thorough neurologic evaluation with partial oculomotor palsies and describe, to our knowledge, the fourth account in the literature of a pupil-sparing third nerve palsy with ipsilateral cerebellar ataxia.
Keywords:Cerebellar ataxia  Claude’s syndrome  Midbrain infarction  Oculomotor nerve palsy
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