| 针刺对MCAO大鼠血NO、ET的影响 |
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| 引用本文： | 王世军,崔可密,卢岩,郭继龙,韩冰冰. 针刺对MCAO大鼠血NO、ET的影响[J]. 山东中医药大学学报, 2005, 29(2): 159-161 |
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| 作者姓名： | 王世军 崔可密 卢岩 郭继龙 韩冰冰 |
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| 作者单位： | 1. 南京中医药大学2002年级博士研究生,江苏,南京,210029
2. 山东中医药大学,山东,济南,250014 |
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| 基金项目： | 山东省卫生厅立项资助 (编号 :1999-4 9) |
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| 摘 要： | 目的 :研究针刺对大脑中动脉阻断 (MCAO)所致局限性脑缺血大鼠血液一氧化氮 (NO)、内皮素 (ET)的影响。方法 :采用穿线法阻断大脑中动脉复制大鼠脑缺血模型 ,研究针刺人中、内关以及曲池、足三里对大鼠血NO、ET的影响 ,并与针刺地机、经渠和假手术组对照。结果 :针刺曲池、足三里和人中、内关均可使慢性脑缺血大鼠血液中升高的NO的水平降至正常 ;地机、经渠针刺组NO的水平低于正常对照和其他针刺组 ;对血ET无明显影响。结论 :针刺人中、内关和曲池、足三里可降低NO的水平。
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| 关 键 词： | 针刺 脑缺血 大鼠 NO ET |
| 文章编号： | 1007-659X(2005)02-0159-03 |
| 修稿时间： | 2004-10-15 |
EFFECTS OF ACUPUNCTURE ON THE BLOOD NO AND ET IN CEREBRAL FOCAL ISCHEMIC RATS CAUSED BY MCAO |
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| WANG Shi-jun,CUI Ke-mi,LU Yan,GUO Ji-long,HAN Bing-bing. EFFECTS OF ACUPUNCTURE ON THE BLOOD NO AND ET IN CEREBRAL FOCAL ISCHEMIC RATS CAUSED BY MCAO[J]. Journal of Shandong University of Traditional Chinese Medicine, 2005, 29(2): 159-161 |
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| Authors: | WANG Shi-jun CUI Ke-mi LU Yan GUO Ji-long HAN Bing-bing |
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| Affiliation: | WANG Shi-jun1,CUI Ke-mi2,LU Yan2,GUO Ji-long2,HAN Bing-bing2 |
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| Abstract: | Objective:to investigate the effects of acupuncture on the serum NO and ET in cerebral focal ischemic rats caused by middle cerebral artery occlusion (MCAO).Methods:MCAO was created by thread embolus,which lead to cerebral focal ischemia in rats.The NO and ET were studied after acupuncture on renzhong(DU26), neiguan(PC6) and quchi(LI11), zusanli(ST36), compared with control group, sham operation group and acupuncture on diji (SP8),jingqu (LU8) group. Results: the NO, that was risen after MCAO, was decreased nearly to the normal level in renzhong, neiguan quchi and zusanli, as was decreased under the normal level in diji,jingqu group. The ET in acupuncture group had no much different with the other groups.Conclusion:acupuncture on renzhong, neiguan, quchi and zusanli can promote the recovery of NO in blood after MCAO. |
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| Keywords: | acupuncture cerebral ischemia rats NO ET |
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