MRI in tick-borne encephalitis |
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Authors: | H Alkadhi S S Kollias |
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Institution: | (1) Institute of Neuroradiology, University Hospital of Zurich, Frauenklinikstrasse 10, Zurich 8091, Switzerland e-mail: kollias@dmr.usz.ch Tel.: + 41 1 255 56 44 Fax: + 41 1 255 45 04, CH |
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Abstract: | The tick-borne encephalitis (TBE) virus gives rise to epidemic encephalitis. Mild forms usually manifest as influenza-like
episodes or are clinically silent. MRI is usually normal in TBE. We describe severe TBE in a patient who presented with fever
and altered mental status after a tick bite and a specific antibody response to TBE. MRI revealed pronounced signal abnormalities
in the basal ganglia and thalamus, without contrast enhancement. These findings coincide well with neuropathological studies
of severe nerve cell degeneration with inflammatory cell infiltrates, neuronophagia and reactive astrocytosis in the deep
grey matter. We review the literature and discuss the relevant differential diagnosis.
Received: 10 November 1999/Accepted: 4 February 2000 |
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Keywords: | Encephalitis tick-borne Magnetic resonance imaging Basal ganglia Thalamus |
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