| 肺结核病人异烟肼乙酰化速率与疗效和副作用的关系 |
| |
| 引用本文： | 刘修琳 彭荣胜. 肺结核病人异烟肼乙酰化速率与疗效和副作用的关系[J]. 郧阳医学院学报, 1996, 15(3): 139-142 |
| |
| 作者姓名： | 刘修琳 彭荣胜 |
| |
| 作者单位： | 郧阳医学院附属太和医院 十堰442000(刘修琳)，十堰市结核病防治所 十堰442000(彭荣胜) |
| |
| 摘 要： | 对286人INH乙酰化速率的测定,快乙酰化者152人;中速乙酰化者71人;缓慢乙酰化者63人;分别为53.15％;24.82％;22.03％。运用含INH周二次方案治疗涂阳肺结核,快速乙酰化者疗末痰菌阴转率为98.46%;缓慢、中间乙酰化者为96.30％,两者无显著性差异。(P>0.05)用此方案均未合用维生素B_6,末见发生末稍神经炎。
|
| 关 键 词： | 异烟肼 乙酰化 疗效 副作用 |
Acetylation of Isoniazid in Pulmonary Tuberculosis |
| |
| Liu Xiulin,Peng Rongsheng. Acetylation of Isoniazid in Pulmonary Tuberculosis[J]. Journal of Yunyang Medical College, 1996, 15(3): 139-142 |
| |
| Authors: | Liu Xiulin Peng Rongsheng |
| |
| Abstract: | Rate of acetylation of isonlazid was measured in 286 adults, of whom 152 were rapid acetylators (53.15%), 71 middle (24. 82%), and 63 slow(22. 03%).Treatment of the smear-postive tuberculosis with INH twice weekly resulted in a 98. 46% negative conversion rate in the rapid, a 99. 30% one in both the middle and slow, with no significant differences between the two (P > 0. 05). During the treatment, no vitamin B6 was administered and no peripheral neuritis occurred. |
| |
| Keywords: | isoniazid acetylation pulmonary tuberculosis |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
