| 生肌愈疡膏的质量标准研究 |
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| 引用本文： | 李佳莉,朱卫丰,唐丽萍,刘星晔,刘水婷. 生肌愈疡膏的质量标准研究[J]. 江西中医药大学学报, 2020, 32(3): 78-82,109 |
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| 作者姓名： | 李佳莉 朱卫丰 唐丽萍 刘星晔 刘水婷 |
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| 作者单位： | 江西中医药大学现代中药制剂教育部重点实验室 南昌 330004;江西省中医院药剂科 南昌 330006 |
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| 摘 要： | 目的:建立生肌愈疡膏的质量标准。方法:采用薄层色谱法对生肌愈疡膏中当归、紫草以及血竭药材进行鉴别;采用高效液相色谱法对血竭素进行含量测定。结果:薄层色谱专属性强,分离度高,阴性对照无干扰;高效液相色谱法测得血竭素在4.54~145.24μg/mL(r=0.9999)范围内进样量与峰面积呈良好的线性关系,平均加样回收率分别为100.93%,RSD为2.53%。结论:所建立的定性、定量方法操作简便,结果准确,重现性好,能够有效控制生肌愈疡膏的质量。
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| 关 键 词： | 生肌愈疡膏 质量标准 血竭 高效液相色谱法 薄层色谱法 |
Study on Quality Standard of Shengji Yuyang Ointment |
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| LI Jia-li,ZHU Wei-feng,TANG Li-ping,LIU Xing-ye,LIU Shui-ting. Study on Quality Standard of Shengji Yuyang Ointment[J]. Journal of Jiangxi College of Traditional Chinese Med, 2020, 32(3): 78-82,109 |
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| Authors: | LI Jia-li ZHU Wei-feng TANG Li-ping LIU Xing-ye LIU Shui-ting |
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| Affiliation: | (Key Laboratory of Modern Chinese Medicine Preparation,Ministry of Education,Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China;Department of pharmacy,Jiangxi Hospital of Traditional Chinese Medicine Nanchang 330006,China) |
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| Abstract: | Objective:To establish the quality standard of Shengji Yuyang Ointment.Methods:Radix Angelicae Sinensis,Radix Arnebiae and Dragon's Blood in Shengji Yuyang Ointment were identified by TLC,and the contents of ferulic acid,beta,beta'-dimethylacryloyl acarbonine(akanin)and dracorhodin were determined by high performance liquid chromatography.Results:TLC had strong specificity,high separation and no interference from negative control.The injection volume and peak area of draconitin in the range of 4.54~145.24 g/mL(r=0.9999)were determined by high performance liquid chromatography.The average recoveries was100.93%(RSD=2.53%,n=6).Conclusion:The established qualitative and quantitative methods are simple,accurate and reproducible,and can effectively control the quality of Shengji Yuyang Ointment. |
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| Keywords: | Shengji Yuyang Ointment Quality Standard Draconis Sanguis HPLC TLC |
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