Chickenpox Chorioretinitis with Retinal Exudates and Periphlebitis |
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| Authors: | Hirokuni Kitamei Kenichi Namba Nobuyoshi Kitaichi Akiko Wakayama Shigeaki Ohno Susumu Ishida |
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| Institution: | aDepartments of Ophthalmology and Health Sciences University of Hokkaido, Sapporo, Japan;bDepartments of Ocular Inflammation and Immunology, Hokkaido University Graduate School of Medicine, and Health Sciences University of Hokkaido, Sapporo, Japan;cDepartment of Ophthalmology, Health Sciences University of Hokkaido, Sapporo, Japan |
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| Abstract: | BackgroundChickenpox is rarely associated with posterior segment inflammation. We report on a case of unilateral chickenpox chorioretinitis with retinal exudates and periphlebitis.Case PresentationA 21-year-old healthy man, who suffered from chickenpox 2 weeks prior to symptom development, exhibited mild anterior chamber cells, vitreous opacity, sheathing of retinal veins, and yellow-white exudates in his right eye. Varicella zoster virus DNA was detected by polymerase chain reaction in the aqueous humor. He was treated with intravenous acyclovir followed by oral prednisolone and valaciclovir. Aqueous cells quickly disappeared and retinal exudates diminished within 1 month, leaving faint retinal scarring. Retinal arteritis had never been observed in this patient.ConclusionsAlthough the ocular findings in this case were similar to acute retinal necrosis (ARN), the clinical features differed from ARN in the following points: (1) mild anterior chamber inflammation, (2) absence of retinal arteritis, and (3) prompt resolution of inflammatory findings. The distinctive clinical features indicated that chorioretinitis associated with chickenpox may not have the same pathological conditions as ARN.Key Words: Chickenpox, Chorioretinitis, Intraocular inflammation, Primary VZV infection, Uveitis, Varicella zoster virus, Acute retinal necrosis |
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