Intravitreal Bevacizumab for Photodynamic Therapy-Induced Massive Macular Detachment in Acute Central Serous Chorioretinopathy |
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Authors: | Maria G Kotoula Fani Zacharaki Evangelia E Tsironi |
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Institution: | Department of Ophthalmology, University of Thessaly School of Medicine, Larissa, Greece |
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Abstract: | We present a long followed up case of acute central serous chorioretinopathy (CSC) complicated by a severe visual loss due to massive pigment epithelium detachment of the macula after a full-dose photodynamic therapy (PDT). Rapid anatomical and functional improvement was observed after a single intravitreal injection of bevacizumab. To our knowledge, we report the first case of PDT-treated CSC complicated by severe visual loss. We can only speculate that the serous detachment of the posterior pole might have been caused by PDT-induced VEGF overexpression, explaining such an impressive response to Avastin treatment.Key Words: Bevacizumab, Central serous chorioretinopathy, Photodynamic therapy |
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