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437例疑似登革热患者急性期血液病毒分离结果及分析
引用本文:梁风屏,杜福,文建华,罗会明,黄满涛. 437例疑似登革热患者急性期血液病毒分离结果及分析[J]. 华南预防医学, 1996, 0(1)
作者姓名:梁风屏  杜福  文建华  罗会明  黄满涛
作者单位:广东省流行病防治研究所
摘    要:1978~1991,广东省登革热流行期间,采集疑似登革热患者急性期血标本437例,其中用新生小白鼠分离145例,阳性30例,阳性率为20.68%;C6/36细胞分离351例,阳性187例,阳性率53.8%,。59份血标本用配对方法检测,表明C6/36细胞分离登革病毒敏感性高于新生小白鼠(P<0.01)。病毒分离结果还表明不同型别的登革病毒对新生小白鼠敏感性不同,同型不同年份分离的登革病毒株对新生小白鼠敏感性也不同。

关 键 词:登革病毒,病毒分离,新生小白鼠,白纹伊蚊C6/36细胞

Isolation of Dengue Viruses from 437 suspectedDengue Fever patients
Liang Feng ping,et al.. Isolation of Dengue Viruses from 437 suspectedDengue Fever patients[J]. South China JOurnal of Preventive Medicine, 1996, 0(1)
Authors:Liang Feng ping  et al.
Affiliation:Institute of epidemic controland prevention of Guangdong province.
Abstract:During the epidemics of Dengue Fever from 1979 to 1991, 437 specimens of acute phase bloodof suspected patients were collected. Of 437 specimens, 145 were inoculated to newborn mice with30 positive.(The specimens found to be isolation rate was 20. 68%), and 351 were inoculated tocell cjone C6/36 of the Aedes Albopictus, with 187 specimens found to be positive (The isolationrate was 53. 8%). The pared test of virus isolation in 59 specimens showed that the sensitivityusing cell clone C6/36 was higher than that using newborn mice (X2= 17. 93. P<0'.01). Therestllts of virus isolation also showed that the sensitivity of dengue viruses to newborn mice wasdifferent in diferent types and even in the same types isolated in different years.
Keywords:Dengue virus Isolation of Virus Newborn mice C6/36 of Aedes Albopictus
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