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BCG制剂降低原发性肾病综合征医院感染率的临床研究
引用本文:赵铖,杨桢华,孙安远,陈战瑞,谢恺庆. BCG制剂降低原发性肾病综合征医院感染率的临床研究[J]. 广西医学, 2002, 24(11): 1725-1726
作者姓名:赵铖  杨桢华  孙安远  陈战瑞  谢恺庆
作者单位:广西医科大学第一附院肾内科,530021
基金项目:美国健康基金会增进人类健康基金资助项目 (合同号 :PSBH 2 0 0 0 11)
摘    要:目的:观察卡介苗(BCG)制剂卡介菌多糖核酸(BCG-PSN)在治疗原发性肾病综合征(PNS)时的医院感染率降低情况。方法:对96例住院患采用随机对照组方法观察比较BCG-PSN治疗组和对照组的医院感染率及尿蛋白量下降程度的变化情况。结果:BCG-PSN治疗组的医院感染率为8.5%,对照组为26.5%,两组间比较在统计学上有显性差异。而尿蛋白量在BCG短疗程治疗中下降程度无差异。结论:BCG-PSN可明显降低PNS的医院感染率。

关 键 词:医院感染 卡介菌多糖核酸 原发性肾病综合征

The clinical research on using BCG-PSN to reduce the nosocomial infection rate of PNS patients
Zhao Chen,Yang Zhenhua,Sun Anyuan,et al The First Affiliated Hospital,Guangxi Medical University. The clinical research on using BCG-PSN to reduce the nosocomial infection rate of PNS patients[J]. Guangxi Medical Journal, 2002, 24(11): 1725-1726
Authors:Zhao Chen  Yang Zhenhua  Sun Anyuan  et al The First Affiliated Hospital  Guangxi Medical University
Affiliation:Nanning 530021
Abstract:Objective:To observe the nosocomial infection rate and the decrease of albuminuria during the process of treatment with Polysaccharide nucleic fraction of Bacillus Calmette Guerin(BCG-PSN) of the primary nephrotic syndrome (PNS) patients. Methods: The nosocomial infection rate and the decrease of albuminuria were observed in 96 PNS inpatients who were allocated randomly into the BCG-PSN study group and the contrlo group.Results: The nosocomial infection rate of BCG-PSN study group was 8.5%,and the rate of control group was 26.5%.There was obvious difference in the nosocomial infection rate between BCG-PSN study group and the control group.There was no difference in the decrease of albuminuria between the two groups.Conclusion: BCG-PSN can obviously reduce the nosocomial infection rate of PNS patients.
Keywords:Nosocomial infection  BCG-PSN  Primary nephrotic syndrome
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