益气活血解毒方治疗急性冠脉综合征介入术后气虚痰浊、瘀毒互结证患者的临床研究

目的 观察益气活血解毒方对正气亏虚、瘀毒互结证的急性冠脉综合征(ACS)冠脉介入术后患者炎症因子的影响.方法 选取辨证为正气亏虚、淤毒互结证的ACS冠脉介入术后患者共80例,随机分为观察组与对照组各40例.对照组予西医规范治疗,观察组加用益气活血解毒方治疗1个月.比较治疗前后检测指标单核细胞趋化蛋白-1(MCP-1)、...

Clinical Study on the Effect of Yiqi Huoxue Jiedu Decoction on the Inflammatory Factors in Patients with Acute Coronary Syndrome after the Treatment of"Qi Deficiency,Phlegm,Turbidity,Stasis and Toxin Syndrome"

Objective:To explore the effect of Yiqi Huoxue Jiedu Decoction on inflammatory factors in patients with acute coronary syndrome after percutaneous coronary intervention with syndromes of"deficiency of qi and deficiency of stasis and toxicity".Methods:A total of 80 patients with acute coronary syndrome after percutaneous coronary intervention who were identified as"deficiency of qi and stasis-toxin syndrome"were randomly divided into the observation group and control group,40 cases in each group.The control group was only given western medicine standard treatment,the observation group was given western medicine standard treatment combined with oral Yiqi Huoxue Jiedu Decoction,and the treatment lasted for 1 month.Before and after treatment,the indicators of monocyte chemoattractant protein-1(MCP-1),interleukin-6(IL-6),C-reactive protein(CRP),total bilirubin(TC),low-density lipoprotein cholesterol(LDL-C),triacylglycerol(TAG),N-terminal pro-brain natriuretic peptide(NT-ProBNP)and left ventricular ejection fraction(LVEF)were measured to observe the clinical efficacy and safety.Results:After treatment,the laboratory indicators MCP-1,IL-6,CRP,TC,LDL-C,NT-ProBNP,and LVEF in the observation group had greater improvements than those in the control group(P<0.05).Conclusion:Yiqi Huoxue Jiedu Decoction can improve inflammatory factors,blood lipids,and cardiac function in ACS patients with"qi deficiency,phlegm,turbidity,and stasis-toxin syndrome"after percutaneous coronary intervention.Its mechanism may be related to regulating body inflammation.The response is related.