| 维拉帕米对糖尿病病人体外血小板聚集的影响 |
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| 引用本文： | 夏邦顺,金小君. 维拉帕米对糖尿病病人体外血小板聚集的影响[J]. 中国新药与临床杂志, 1995, 0(2) |
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| 作者姓名： | 夏邦顺 金小君 |
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| 作者单位： | 中国人民解放军广州军区武汉总医院内分泌科，湖北医科大学第二附属医院血液室 |
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| 摘 要： | 糖尿病Ⅱ型病人２０例（男性１０例，女性１０例，年龄５８±ｓ７ａ）在０．５μｍｏｌ／ＬＡＤＰ作为血小板致聚条件下加入０．２５－１．０μｍｏｌ／Ｌ维拉帕米，观察对体外血小板聚集的影响。结果表明糖尿病Ⅱ型病人在二相聚集比正常者显著增强，维拉帕米在０．２５－１．０μｍｏｌ／Ｌ浓度范围内均可部分减缓糖尿病Ⅱ型病人所增高的血小板聚集。
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| 关 键 词： | 维拉帕米；非胰岛素依赖型糖尿病；腺苷二磷酸；血小板聚集 |
Effect in vitro of verapamil on platelet aggregation of diabetic patients |
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| XIA Bang-Shun. Effect in vitro of verapamil on platelet aggregation of diabetic patients[J]. Chinese Journal of New Drugs and Clinical Remedies, 1995, 0(2) |
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| Authors: | XIA Bang-Shun |
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| Abstract: | Selecting 20 patients with non-insulin-dependent diabetes millitus (M10,F 10,age 58±s 7 a),we evaluated the effect of verapamil 0.25-1.0μmol/L on the platelet aggregation induced by ADP 0.5μmol/L in vitro.The results showed that the increased platelet aggregation,especially in second phase,was partly suppressed by verapamil 0.25-1.0μmol/L. |
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| Keywords: | verapamil non-insulin-dependent diabetes mellitus adenosine diphosphate platelet aggregation |
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