| 广西孕妇乙型肝炎病毒宫内感染及其危险因素的研究 |
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| 引用本文： | 梁浩,邬质彬,郭湘碧,徐国城. 广西孕妇乙型肝炎病毒宫内感染及其危险因素的研究[J]. 广西医科大学学报, 1999, 16(3): 251-253 |
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| 作者姓名： | 梁浩 邬质彬 郭湘碧 徐国城 |
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| 作者单位： | 1. 广西医科大学流行病学教研室,南宁,530021
2. 广西妇幼保健院 |
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| 摘 要： | 目的：为深入揭示乙型肝炎病毒（ＨＢＶ）宫内感染及其危险因素。方法：采用多聚酶链反应（ＰＣＲ）结合酶联免疫吸附法（ＥＬＩＳＡ）对广西１１６例ＨＢｓＡｇ阳性和５２例ＨＢｓＡｇ阴性孕妇外周血及其引产胎儿胎心血进行ＨＢＶ血清学樗狐和ＨＢＶ ＤＮＡ检测。结果：ＨＢｓＡｇ阳性、ＨＢｓＡｇ和ＨＢｅＡｇ双阳性、ＨＢＶ ＤＮＡ阳性孕妇肺儿ＨＢＶ ＤＮＡ检出率（５１．３％、９０．２％、８３．８％）均分别显著高于对照组
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| 关 键 词： | 乙型肝炎病毒 宫内感染 Logistic回归 PCR |
| 修稿时间： | 1998-10-05 |
A STUDY ON THE HEPATITIS B VIRUS INTRAUTERINE INFECTION AND ITS RISK IN GUANGXI |
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| Liang Hao,Wu Zhibin,Guo Xiangbi,et al. A STUDY ON THE HEPATITIS B VIRUS INTRAUTERINE INFECTION AND ITS RISK IN GUANGXI[J]. Journal of Guangxi Medical University, 1999, 16(3): 251-253 |
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| Authors: | Liang Hao Wu Zhibin Guo Xiangbi et al |
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| Abstract: | Objective: To go further into the hepatitis B virus (HBV) intrauterine infection and its risk factors Method: HBV serum markers and HBV DNA were detected by using enzyme linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR) in 116 HBsAg positive and 52 HBsAg negative motherinduced abortion foetuses Results: The positive rates of HBV DNA in the heart blood of foetuses from HBsAg positive pregnant women,HBsAg and HBeAg positve pregnant women and HBV DNA positive pregnant women were 513%,902% and 838%,respectively,which were significantly higher than those (39%,212%,00%) of controlsHBsAgHBeAgHBV DNA and gestational period were selected as risk factors of HBV intrauterine infection by Logistic regression Conclusion: The HBV intrauterine infection rate is rather high in GuangxiHBsAg negative pregnant women may also transmit HBV intrauterine infectionThe main risk factors of HBV intrauterine infection are HBV DNA,HBeAg,gestational period and HBsAg in ORvalue order |
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| Keywords: | hepatitis B virus intrauferine infection polymerase chain reaction Logistic regression |
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