血液透析与肾移植对心脏结构的影响

目的 了解血液透析与肾移植对尿毒症患心脏结构的影响。方法 通过对七名慢性肾功能衰竭尿毒症患在接受治疗前、接受血液透析6个月后以及。肾移植3个月后，行自身对照，对左心室、左心房大小及其它可能影响心脏结构的因素如血压、血色素、尿素氮等进行检测和分析。结果 血液透析可以改善贫血状态和尿毒症毒素水平，但对左心房、左心室结构影响不大。而肾移植可彻底纠正贫血和清除尿毒症毒素，并可使扩大的左心房、左心室缩小。高血压在血液透析和肾移植无差别。结论 在影响尿毒症心脏改变的多种因素中，贫血与尿毒症毒素较高血压等因素更为重要。

The influence of hemodialysis and kidney transplantation on cardiac structure in uremic patients

Objective To observe the influence of hemodialysis and kidney transplantation on cardiac structure in uremic patients. Methods Seven patients were studied before treatment, 6 month later of hemodialysis and 3 month later of kidney transplantation. The left ventricular and atrium size and many factors, such as blood pressure, hemoglobin, urea nitrogen, which may influenced on cardiac structure were measured and analyzed. Results There were no significant difference of hypertension before and after treatment. The degree of anemia and the level of uremic toxin in blood were improved partially by treatment of hemodialysis, there were no significant changes of left ventricular and atrium size before and after hemodialysis. But all of the factors, such as anemia, uremic toxin except hypertension were thoroughly corrected and the size of left ventricular and atrium significantly decreased after kidney transplantation. Conclusion The anemia and uremic toxins are more important factors than hypertension on influencing left cardiac chamber size of uremic patients.