| 小儿感冒舒颗粒中荆芥挥发油β-环糊精包合的工艺研究 |
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| 引用本文： | 赵开军,濮存海,关志宇.小儿感冒舒颗粒中荆芥挥发油β-环糊精包合的工艺研究[J].中药材,2006,29(2):181-184. |
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| 作者姓名： | 赵开军 濮存海 关志宇 |
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| 作者单位： | 南京中山制药厂技术中心,江苏,南京,210012 |
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| 摘 要： | 目的:研究小儿感冒舒颗粒中β-环糊精包合荆芥挥发油的最佳工艺。方法:利用正交实验法,考察β-环糊精与挥发油的配比、包合温度、包合时间3个因素对挥发油利用率、包合物含油率的影响。结果:最佳包合工艺为:荆芥油:β-环糊精(1m l∶10 g)、包合温度60℃、包合时间3 h。结论:该工艺简便、易行,可用于大生产。
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| 关 键 词： | 荆芥挥发油 β-环糊精包合物 正交实验设计 |
| 文章编号： | 1001-4454(2006)02-0181-04 |
| 收稿时间： | 2005-09-12 |
| 修稿时间： | 2005年9月12日 |
Study on the Process of Inclusion Volatile Oil of Herba Schizonepetae with β-cyclodextrin from Xiao'er Ganmaoshu Granule |
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| ZHAO Kai-jun,PU Cun-hai,GUAN Zhi-yu.Study on the Process of Inclusion Volatile Oil of Herba Schizonepetae with β-cyclodextrin from Xiao''''er Ganmaoshu Granule[J].Jorunal of Chinese Medicinal Materials,2006,29(2):181-184. |
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| Authors: | ZHAO Kai-jun PU Cun-hai GUAN Zhi-yu |
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| Institution: | Najing Zhongshan Pharmaceutical Factory, Najing 210012, China |
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| Abstract: | OBJECTIVE: To study optimum inclusion process condition for volatile oil with beta-cyclodextrin (beta-CD). METHODS: The optimum preparation condition were investigated by orthogonal design. The influence of utilization beta-CD and oil, inclusion temperature and time were studied to determin the utilization ratio of volatile oil and oil-bearing rate. RESULTS: The optimum preparation conditions were established as: volatile oil: beta-CD was 1:10, the inclusion temperature was 60 degrees C and inclusion time was 3h. CONCLUSION: The method is convenient and can he used for mass production. |
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