| PET在精神分裂症中的研究进展 |
| |
| 引用本文： | 蔡莉,高硕. PET在精神分裂症中的研究进展[J]. 国际放射医学核医学杂志, 2011, 35(2): 69-72. DOI: 10.3760/cma.j.issn.1673-4114.2011.02.002 |
| |
| 作者姓名： | 蔡莉 高硕 |
| |
| 作者单位： | 天津医科大学总医院PET-CT中心,300052 |
| |
| 摘 要： | PET是一种可以用于评估大脑代谢活性、血流及确定人脑中重要的神经递质分布的功能神经影像工具.与传统影像技术相比,PET能够借助不同的示踪剂定性、定量地分析大脑葡萄糖代谢、血流、多巴胺及5-羟色胺神经递质和受体的分布及活性改变,因此广泛用于精神分裂症的神经生化及病理生理学机制的研究.该文通过不同的放射性示踪剂,简要综述P...
|
| 关 键 词： | 正电子发射断层显像术 受体,多巴胺 受体,血清素 精神分裂症 认知障碍 |
Progress of PET imaging in Schizophrenia |
| |
| CAI Li,GAO Shuo. Progress of PET imaging in Schizophrenia[J]. International Journal of Radiation Medicine and Nuclear Medicine, 2011, 35(2): 69-72. DOI: 10.3760/cma.j.issn.1673-4114.2011.02.002 |
| |
| Authors: | CAI Li GAO Shuo |
| |
| Abstract: | PET is an important functional neuroimaging technique that can be used to assessment of cerebral metabolic activity and blood flow and identifies the distribution of important neurotransmitters in the human brain. Compared with other conventional imaging techniques, PET enables regional cerebral glucose metabolism, blood flow, dopaminergic and serotonergic receptor function to be assessed qualitatively and quantitatively. In recent years, PET increasingly being used greatly to advance our understanding of the neurobiology and pathophysiology of schizophrenia. This review focuses on the use of PET tracers in identifying regional brain abnormalities and regions associated with cognitive functioning in schizophrenia. |
| |
| Keywords: | Positron-emission tomography Receptors,dopamine Receptors,serotonin Schizophrenia Cognition disorders |
| 本文献已被 万方数据 等数据库收录！ |
|
