蛋白质组学及其在寄生虫学中的应用

随着多种生物基因组测序计划的完成,应用蛋白质组学方法在整体水平上研究复杂生命现象的后基因组时代已经到来.蛋白质是生物生长、分化、代谢及调控的主要执行者,因而蛋白质组学方法成为研究生物体不同状态下差异蛋白表达非常重要的技术手段.差异蛋白质组学主要用于筛选和鉴定不同种类和状态下各样本之间蛋白质组之间的区别和变化,寻找任何有...

Proteomics and its application in parasitology

With the completion of many genome sequencing projects of organisms, the post-genomic era has arrived with the application of proteomics in the overall level of complexity of life. Protein is the executor of biological growth, differentiation, metabolism and regulation, and thus it becomes a very important technical method in examination of the differential protein expression of organism under different conditions. Differential proteomics is mainly used for selection and identification of the differences and changes between the proteins at the different types and state of samples, looking for any significant factors that cause the difference in protein spectrum of the sample, thus to understand the development and change of individual physiology. The proteome of some parasites has developed rapidly as a branch of proteomics. In this paper, we reviewed the differential proteomics applied in parasite research.