慢性阻塞性肺疾病急性加重期病原学特点及治疗对策的研究

目的 了解慢性阻塞性肺疾病急性加重期患者病原学特点及耐药情况,为临床治疗慢性阻塞性肺疾病急性加重期患者提供对策,更好的合理选用抗生素.方法 采用回顾性的研究方法,分析本院2008年3月至2010年3月因慢性阻塞性肺疾病急性加重期入院患者病原学特点,常用药物的耐药性以及治疗对策.结果 慢性阻塞性肺疾病急性加重期患者细菌感...

Studies on the pathogen characteristics and treatment strategies of chronic obstructive pulmonary disease patients in the period of acute exacerbation

Objective By understanding etiology and drug resistance characteristics of acute exacerbation of chronic obstructive pulmonary disease (AECOPD),we can provide a solution to better rational use of antibiotics for the clinical tratment of patients with AECOPD.Methods By retrospective research methos,we analysis pathogen characteristics,commonly drug resistance and treatment strategies of AECOPD patients admitted to our hospital from march 2008 to March 2010.Results The bacterial infection positive rate of AECOPD patients is 82.8%,and to Gram-negative bacteria,bacterial infection rate.There is high cure rate whenβ-lactamase inhibitor compound and carbapenem antibiotics are used treatment.Conclusions AECOPD bacterial infection is more common,and etiology is complex (with G-bacilli,resistance rate).There is a high cure rate by making selection based onβ-lactamase inhibitor compound and carbapenem antibiotics in the absence of bacteriological treatment prior.Be based on a bacteriological and susceptibility tests,we can adjust the antibiotics to reduce the generation of resistant bacteria.