| CD4+CD25+调节性T细胞在艾滋病病毒感染中的作用 |
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| 引用本文： | 刘金峰,李凌华,唐小平.CD4+CD25+调节性T细胞在艾滋病病毒感染中的作用[J].国际流行病学传染病学杂志,2011,38(3):179-182. |
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| 作者姓名： | 刘金峰 李凌华 唐小平 |
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| 作者单位： | 广州医学院附属市八人民医院传染病研究所,510060 |
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| 基金项目： | 国家"十一五"科技重大专项 |
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| 摘 要： | CD4+CD25+调节性T细胞(Tregs)是一类具有特殊免疫调节功能的T细胞亚群,是Tregs的重要组成部分,参与多种感染性疾病的免疫应答,在病毒感染的慢性化、免疫病理、阻止自身免疫应答和维持机体免疫平衡等方面发挥重要的作用.此文就CD4+CD25+Tregs在HIV感染进程中的作用作了综述.
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| 关 键 词： | T淋巴细胞 调节性 HIV 免疫抑制 |
Role of CD4+ CD25+ regulatory T cells in human immunodeficency virus infection |
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| LIU Jin-feng,LI Ling-hua,TANG Xiao-ping.Role of CD4+ CD25+ regulatory T cells in human immunodeficency virus infection[J].International Journal of Epidemiology and Infectious Disease,2011,38(3):179-182. |
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| Authors: | LIU Jin-feng LI Ling-hua TANG Xiao-ping |
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| Abstract: | CD4+CD25+ regulatory T cells (Tregs) is a group of T lymphocyte subsets possessing specific functions in immunological regulation and appear to be critical components of Tregs, which participate in the immune response to multiple infectious diseases. CD4+ CD25+ Tregs play significant roles in the chronicity of virus infection, immunopathogenesis, prevention of autoimmune response and maintenance for the immunologic balance. The role of CD4+ CD25 + Tregs in the disease progression of HIV infection is reviewed in this article. |
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| Keywords: | T lymphocytes regulatory HIV Immunosuppression |
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