Development of specific immunoglobulin Ga (IgGa) and IgGb antibodies correlates with control of parasitemia in Babesia equi Infection |
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| Authors: | Cunha Cristina W McGuire Travis C Kappmeyer Lowell S Hines Stephen A Lopez A Marianela Dellagostin Odir A Knowles Donald P |
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| Affiliation: | Washington State University, Department of Veterinary Microbiology and Pathology, Pullman, WA 99164-7040, USA. cwcunha@vetmed.wsu.edu |
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| Abstract: | In this study, the kinetics of specific immunoglobulin G (IgG) isotypes were characterized in Babesia equi (Theileria equi)-infected horses. IgGa and IgGb developed during acute infection, whereas IgG(T) was detected only after resolution of acute parasitemia. The same IgG isotype profile induced during acute infection was obtained by equi merozoite antigen 1/saponin immunization. |
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