疏肝和胃降逆汤联合莫沙必利治疗胆汁反流性胃炎的临床分析

目的:探讨疏肝和胃降逆汤与莫沙必利联合应用于胆汁反流性胃炎治疗的临床效果。方法:收集医院近年来于本院门诊治疗的127例胆汁反流性胃炎病例,两组均服用莫沙必利,同时口服硫糖铝。观察组在上述基础上同时口服自拟疏肝和胃降逆汤。对临床症状的改善进行评分,其考察的指标主要有恶心呕吐、腹痛腹胀、泛酸嗳气等症。同时参照《中医内科学》及《实用消化病诊疗学》中的标准对临床症状缓解或消失时间及总体临床疗效进行比较。结果:联合疏肝和胃降逆汤观察组治疗后痊愈率、总有效率分别达52.4%、93.9%,而无效率仅2.4%,均显著优于西医常规治疗对照组(P<0.05)。且观察组经治疗后食欲不振、恶心呕吐、腹痛腹胀等临床症状较对照组显著缩短,临床症状评分平均为(12.2±3.5)分,均显著优于对照组(P<0.05)。结论:疏肝和胃降逆汤与莫沙必利联合治疗胆汁反流性胃炎的临床效果明显,具有重要的临床意义。

Shugan Hewei Jiangni Decoction Combined with Mosapride in Treatment of Bile Reflux Gastritis

Objective： To investigate the clinical effect of Shugan Hewei Jiangni Decoction combined with Mosapride in the treatment of bile reflux gastritis. Methods： In our hospital in recent years,127 cases of bile reflux gastritis patients were given Mosapride and sucralfate orally. The observation group on the basis added Shugan Hewei Jiangni Decoction.The clinical symptom score improvement was evaluated. The indicators were nausea and vomiting,abdominal pain and distension,pantothenic acid eructation. With reference to the Traditional Chinese Medicine and Practical Internal Medicine Diagnosis and Treatment of Digestive Diseases,the clinical symptoms relieved or disappeared clinical time and overall comparison were observed. Results： The treatment group cure rate＇s total efficiency was 52. 4% and 93. 9% respectively and the inefficiency was only 2. 4%,significantly better than that of the routine treatment in Western medicine control group（ P〈0. 05）. And we observed the clinical symptoms after treatment. The loss of appetite,nausea and vomiting,abdominal pain and distension were significantly relieved than those of the control group and the clinical symptoms score was12. 2 ± 3. 5 which was significantly higher than that in the control group（ P〈0. 05）. Conclusion： The clinical effect of Shugan Hewei Jiangni Decoction combined with Mosapride in the treatment of bile reflux gastritis has important clinical significance.