铁皮石斛原球茎的化学成分研究

 目的 研究铁皮石斛原球茎的化学成分。方法 应用色谱技术分离铁皮石斛原球茎中的化学成分,通过理化常数和波谱分析鉴定化合物的结构。 结果 从乙醇提取物的丙酮、三氯甲烷和95%乙醇三部分分离得到8个化合物,分别鉴定为：1-O- p-阿魏酰基-β-D-吡喃葡萄糖苷（Ⅰ）,arillatose B（Ⅱ）,4-(β-D-吡喃葡萄糖基)苄醇（Ⅲ）,4-羟甲基-2,6-二甲氧基苯基-β-D-吡喃葡萄糖苷（Ⅳ）,三十六烷酸（Ⅴ）,二十七烷醇（Ⅵ）,β-谷甾醇（Ⅶ）,3β,25-二羟基-23-烯-环菠萝蜜烷（Ⅷ）。结论 以上化合物均为首次从铁皮石斛原球茎中分得。其中,化合物Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅷ为首次从石斛属中分得。

Study on Chemical Components of Dendrobium officinale Protocorm

OBJECTIVE To study the chemical constituents of Dendrobium officinale protocorm. METHODS The compounds were isolated and purified by means of column chromatography,and their structures were identified on the basis of spectroscopic data and comparison with standard literature data. RESULTS Eight compounds were isolated from the(CH₃)₂CO,CHCl₃ and 95% EtOH fractions of the EtOH extract,and identified as 1-O-p-feruloyl-β-D-glucopyranoside(Ⅰ), arillatose B(Ⅱ),4-(β- D-glucopyranosyloxy)benzyl alcohol(Ⅲ),4-hydroxymethyl-2,6-dimethoxyphenyl-β-D-glucopyranoside(Ⅳ), n-hexatriacontanoic acid(Ⅴ),n-heptacosanol(Ⅵ),β-sitosterol(Ⅶ),and cycloart-23-ene-3β,25-diol(Ⅷ). CONCLUSION All these compounds were isolated from the protocorms of D.officinale for the first time. CompoundsⅠ,Ⅱ,Ⅲ,Ⅳ,and Ⅷ were obtained from Dendrobium genus for the first time.