Mannitol and dopamine in patients undergoing cardiopulmonary bypass: a randomized clinical trial |
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| Authors: | Carcoana Olivia V Mathew Joseph P Davis Elizabeth Byrne Daniel W Hayslett John P Hines Roberta L Garwood Susan |
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| Affiliation: | Department of Anesthesiology, Yale University School of Medicine, New Haven, Connecticut 06520-8051, USA . |
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| Abstract: | In this prospective, randomized, placebo-controlled, double-blinded study, we determined the effects of two commonly used adjuncts, mannitol and dopamine, on beta(2)-microglobulin (beta(2)M) excretion rates in patients undergoing coronary artery bypass graft surgery with cardiopulmonary bypass (CPB). beta(2)M excretion rate has been described as a sensitive marker of proximal renal tubular function. One-hundred patients with a preoperative serum creatinine level
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