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血清同型半胱氨酸高水平的老年高血压病患者尿微量白蛋白的变化
引用本文:周英智,马丽娜,杨伟,钱玉英,李耘,冯明. 血清同型半胱氨酸高水平的老年高血压病患者尿微量白蛋白的变化[J]. 心脏杂志, 2014, 26(2): 152-153
作者姓名:周英智  马丽娜  杨伟  钱玉英  李耘  冯明
作者单位:(首都医科大学宣武医院综合科,北京 100053)
基金项目:教育部人文社会科学研究基金项目资助(12YJCZH146)
摘    要:目的:了解老年高血压病患者血清同型半胱氨酸(homocysteine,Hcy)高水平的老年高血压病患者尿微量白蛋白的变化。方法:对120例老年高血压病患者进行血清Hcy的测定及动态血压的测定,高Hcy组59例,正常Hcy组61例,比较两组尿微量白蛋白的水平。结果:高Hcy组患者尿微量白蛋白显著高于正常Hcy组[(22±4)μg/min vs.(15±4)μg/min,P0.01]。结论:高Hcy组高血压病患者尿微量白蛋白升高,Hcy加重高血压病患者的肾损害。

关 键 词:高血压,原发性   同型半胱氨酸   尿微量白蛋白   老年人
收稿时间:2013-08-25

Changes of urinary microalbumin levels in elderly patients with essential hypertension and high homocysteine levels
ZHOU Ying-zhi,MA Li-na,YANG Wei,QIAN Yu-ying,LI Yun,FENG Ming. Changes of urinary microalbumin levels in elderly patients with essential hypertension and high homocysteine levels[J]. Chinese Heart Journal, 2014, 26(2): 152-153
Authors:ZHOU Ying-zhi  MA Li-na  YANG Wei  QIAN Yu-ying  LI Yun  FENG Ming
Affiliation:(Department of Geriatrics, Xuanwu Hospital, Capital Medical University, Beijing 100053, China)
Abstract:AIM: To explore the changes of urinary microalbumin levels in elderly patients with essential hypertension with high homocysteine levels. METHODS: Serum homocysteine and ambulatory blood pressure were measured in 120 elderly patients with hypertension. The patients were divided into two groups: high Hcy group (n =59) and control group (n =61 ), and urinary nficroalbumin was compared between groups. RESULTS: The urinary microalbumin in high Hcy group was higher than in control group [(22±4)μg/min vs. (15±4)μg/min,P〈0.01]. CONCLUSION: High urinary microalbumin in Hey group suggests that Hey increases renal damage in elderly patients with essential hypertension.
Keywords:hypertension, essential  homocysteine  urinary microalbuminuria  elderly
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