| 细胞炎症因子与外风侵袭肝风内动型抽动障碍的相关性研究 |
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| 引用本文： | 罗健兴,吴敏,靳令经.细胞炎症因子与外风侵袭肝风内动型抽动障碍的相关性研究[J].上海中医药大学学报,2014(2):44-46. |
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| 作者姓名： | 罗健兴 吴敏 靳令经 |
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| 作者单位： | [1]同济大学附属同济医院神经内科,上海200065 [2]上海交通大学医学院附属新华医院中医科,上海200092 |
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| 基金项目： | 国家自然科学基金资助项目（81072842）;上海市中医药事业三年行动计划重大项目（ZYSNXD-CC-ZDYJ005）;上海市卫生局基金项目（2010L069A） |
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| 摘 要： | 目的:探讨抽动障碍(TD)发病与细胞炎症因子的相关性。方法:选取40例外风袭肺肝风内动型TD患儿(TD组)及24名健康儿童(对照组)。采用化学发光法检测两组血浆细胞炎症因子TNF-α、IL-2、IL-6和IL-1β水平。结果:TD组患儿血浆TNF-α、IL-2水平高于对照组(P0.05);TD组患儿IL-6水平升高的例数多于对照组(P0.05),但两组IL-1β水平升高的例数无统计学差异(P0.05)。结论:TD发病与细胞炎症因子水平升高密切相关。
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| 关 键 词： | 抽动障碍 细胞炎症因子 外风袭肺 肝风内动 相关性研究 |
Relationship between Inflammatory Cytokines and Tic Disorder of Endogenous Liver Wind Type Caused by External Wind Invasion |
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| Institution: | LUO Jian-xing WU Min JING Ling-jing( 1. Tongji Hospital Affiliated to Tongji University 2. Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine) |
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| Abstract: | Objective： To explore the correlation between attack of tic disorder （TD） and inflammatory cytokiues. Methods： Forty children with TD of endogenous liver wind type （TD group） and 24 healthy children （control group） were enrolled in this study. The levels of TNF-α, IL-2, IL-6 and IL-1β were observed by chemil method. Results The levels of TNF-α and IL-2 in TD group were higher than those of the control group （ P 〈 0.05 ） ; the IL-6 level of the cases in TD group was higher than that of the control group （ P 〈 0.05 ）, and without significant difference in IL-1β level between the two groups （ P 〉 0.05 ）. Conclusion ： The onset of TD is closely related to the rise of inflammatory eytokines level. |
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| Keywords: | tic disorder （TD） inflammatory cytokine invasion of external wind endogenous liver wind correlative study |
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