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认知功能损害与踝臂指数相关性研究
引用本文:简文佳,时晶,倪敬年,魏明清,田金洲.认知功能损害与踝臂指数相关性研究[J].辽宁中医药大学学报,2014(6):75-77.
作者姓名:简文佳  时晶  倪敬年  魏明清  田金洲
作者单位:北京中医药大学东直门医院,北京100007
基金项目:国家重大新药创制平台项目(2011ZX09302-006-01); 北京市科委项目(Z111107056811043); 教育部高等学校学科创新引智基地项目(B08006); 北京中医药大学创新团队项目(2011-CXTD-21); 2013年北京中医药大学自主选题资助项目(2013-JYBZZ-XS-131)
摘    要:目的:探讨踝臂指数(ABI)评价老年人认知功能损害的临床价值。方法:共选取86例住院患者纳入研究,对符合研究标准的患者进行ABI测量、病史采集及常规实验室指标检查,采用简易精神状态量表(MMSE)评估患者认知功能,主要观察MMSE与ABI、临床指标的相关性。结果:认知正常组1.01±0.24与认知损害组0.96±0.19之间ABI有显著性差异(P0.05),MMSE与ABI存在相关性(P0.05)。结论:认知功能损害的患者存在ABI降低,可能与动脉硬化引起靶器官损害有关。

关 键 词:踝臂指数  认知功能  痴呆

Clinical Study on Correlation of Ankle-Brachial Index with Cognitive Impairment
JIAN Wenjia,SHI Jing,NI Jingnian,WEI Mingqing,TIAN Jinzhou.Clinical Study on Correlation of Ankle-Brachial Index with Cognitive Impairment[J].Journal of Liaoning University of Traditional Chinese Medicine,2014(6):75-77.
Authors:JIAN Wenjia  SHI Jing  NI Jingnian  WEI Mingqing  TIAN Jinzhou
Institution:( Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100007, China )
Abstract:Objective : This study aimed to examine the relationship between ankle-brachial index( ABI ) and cognitive impairment in elderly. Methods: We studied 86 in-patients who were referred to Dongzhimen Hospital. All the patients underwent ABI measurement,mini-mental state examination ( MMSE ),laboratory examination and history collection. The tin,relation between ABI and cognitive impairment were analysed. Results : There was significant difference between normal cognitive ( 1.01 ± 0.24 ) and cognitive impairment ( 0.96 ± 0.19 ). And MMSE was positively correlated with ABI ( P〈0.05 ). Conclusion : ABI can predict the cognitive impairment, which may be associated with target organ damages caused by atheroselerosis.
Keywords:ankle brachial index  cognitive function  dementia
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