| 中药固体自乳化药物传递系统的发展及应用简 |
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| 引用本文： | 靖博宇,郑霞,杨瑞,赵佳,金薇,于绍军. 中药固体自乳化药物传递系统的发展及应用简[J]. 辽宁中医药大学学报, 2014, 0(3): 214-216 |
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| 作者姓名： | 靖博宇 郑霞 杨瑞 赵佳 金薇 于绍军 |
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| 作者单位： | 辽宁省中医药研究院制剂中心,辽宁沈阳110034 |
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| 摘 要： | 将液态或半固体的自乳化（SE）组分固化而形成的固体自乳化药物传递系统（S-SEDDS）,可显著提高难溶性药物的生物利用度。该文综述中药固体自乳化系统的特点、辅料选择、在难溶性中药制剂的应用及发展前景。
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| 关 键 词： | 固体自乳化药物传递系统 中药 辅料 生物利用度 |
Development and Application of Solid Self-emulsify in Drug Delivery System on Traditional Chinese Medicine |
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| JING Boyu,ZHENG Xia,YANG Rui,ZHAO Jia,JIN Wei,YU Shaojun. Development and Application of Solid Self-emulsify in Drug Delivery System on Traditional Chinese Medicine[J]. Journal of Liaoning University of Traditional Chinese Medicine, 2014, 0(3): 214-216 |
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| Authors: | JING Boyu ZHENG Xia YANG Rui ZHAO Jia JIN Wei YU Shaojun |
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| Affiliation: | ( Pharmaceutieal Centre, Liaoning Institute of Traditional Chinese Medicine, Shenyang 110034, Liaoning, China ) |
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| Abstract: | The oral bioavailability of water-insoluble drug carl be enhanced significantly by the utilization of solid SEDDS （ S-SEDDS ） or preparing solidification of liquid selfemulsifying （ SE ） ingredients into powders. This article gives an overview of the eharacterizeation, excipients and the application in the field of traditional Chinese medicine as well as the development of S-SEDDS in a systemic way. |
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| Keywords: | solid self-emulsifying drug delivery system traditional Chinese medicine excipien/s bioavailability |
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