| 黑地黄丸及其各单味药HPLC指纹图谱研究简 |
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| 引用本文： | 孙响波,于妮娜,张法荣.黑地黄丸及其各单味药HPLC指纹图谱研究简[J].辽宁中医药大学学报,2014(1):64-65. |
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| 作者姓名： | 孙响波 于妮娜 张法荣 |
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| 作者单位： | [1]山东中医药大学,山东济南250011 [2]山东中医药大学附属医院,山东济南250011 |
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| 基金项目： | 山东省科技发展计划项目（2010G0020214） |
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| 摘 要： | 目的：建立黑地黄丸及其各单味药指纹图谱，探讨黑地黄丸复方水煎液与各单味药化学成分的异同。方法：水煎煮法制备黑地黄丸及其各单味药供试液，HPLC法建立其指纹图谱，对各色谱峰的归属进行分析，比对黑地黄丸复方水煎液与各单味药指纹图谱中药物化学成分的异同。结果：在黑地黄丸复方水煎液指纹图谱中共检出65个药源性成分，1个为煎煮后的化合产物。结论：黑地黄丸复方水煎液与各单味药指纹图谱中药物化学成分存在差异，复方经水煎煮后有新的化合产物生成。
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| 关 键 词： | 黑地黄丸 药物化学成分 HPLC 指纹图谱 |
HPLC Fingerprint of Black Dihuang Pill and Its Single Herbs |
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| SUN Xiangbo,YU Ni＇na,ZHANG Farong.HPLC Fingerprint of Black Dihuang Pill and Its Single Herbs[J].Journal of Liaoning University of Traditional Chinese Medicine,2014(1):64-65. |
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| Authors: | SUN Xiangbo YU Ni＇na ZHANG Farong |
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| Institution: | 1.Shandong University of Traditional Chinese Medicine, Ji＇nan 250011, Shandong, China; 2. Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Ji＇nan 250011, Shandong, China ) |
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| Abstract: | Objective：To establish the Black Dihuang Pill and its single herbs fingerprint, and to discuss the similarities and differences of the water decoction and each single herbs. Methods ： Chinese herbs were tested by HPLC method to establish the fingerprint. The attribution of each chromatographic peak was analyzed, and similarities and differences of chemical composition of Black Dihuang Pill water decoction and each single herbs were studied. Results ： Black Dihuang Pill water decoction fingerprint tested 65 drug- induced constituents, 1 for decoction combined product. Conclusion ： Black Dihuang Pill water decoction and each single herbs fingerprints had chemical composition differences. There was new generated product after water decoction. |
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| Keywords: | Black Dihuang Pill chemical drugs HPLC fingerprint |
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