滋阴益气活血熄风通络法治疗糖尿病周围神经病变的临床观察

目的:观察滋阴益气活血熄风通络法治疗糖尿病周围神经病变的临床疗效。方法:将入选病人随机分为治疗组和对照组各20例,两组中医辨证均属于气阴两虚兼有血瘀型糖尿病周围神经病变(DPN)患者。治疗组服用降糖舒络方,对照组服用弥可保片。治疗前后观察症状积分及糖代谢情况。结果:治疗组病人临床疗效和临床主要症状改善与对照组疗效相当(P>0.05),但是治疗组对次要症状改善均优于对照组(P<0.01)。治疗组对空腹血糖(FBG)、餐后血糖(PBG)疗效不如对照组(P>0.05),但是治疗组糖化血红蛋白(HbA1C)的疗效明显优于西药组(P<0.05)。结论:滋阴益气活血熄风通络法可能通过改善糖代谢、抑制醛糖还原酶活性及改善微循环而起到治疗DPN的作用。

The Clinical Observation of Nourishing Yin,Invigorating Qi,Promoting Blood Circulation,Extinguishing Wind and Draining Collateral Method Treat DPN

Objective ：To observe the clinical effect of nourishing Yin, invigorating Qi, promoting blood circulation, extinguishing wind and draining collateral method treat DPN. Methods ： The selected patients were randomly divided into treatment groups and control group, each group has 20 patients normal group, The two groups DPN patients all were belonged to symptoms of accumulation of blood, deficiency of both Qi and Yin. The treatment group patients take Jiangtangshuluo formula, the control group patients take methyeobal tablets,observe the symptoms integral and the sugar metabolism before treatment and after treatment. Re- sults：The curative effect and the main clinical symptoms improvement of the treatment group patients equaled with the control group（P 〉 O. 05） ,but the curative effect of the treatment group to secondary symptoms were better than the control group（ P 〈0. 01 ）. The effect to FBG, PBG of the treatment was not better than the control group（ P 〉0. 05 ）, but the effect to HbAlC was better than the west medicine group obviously（P 〈0.05 ）. Conclusion：Nourishing Yin, invigorating Qi, promoting blood circulation, extinguishing wind and draining collateral method treat DPN by improving sugar metabolism and micro circulation, inhibiting the activity of aldose reductase maybe.