| SOD、Vc和Zn对老年性白内障大鼠晶状体中Na-K ATP酶、Mg-ATP酶活性的影响 |
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| 引用本文： | 杨笑天,邢进,张涤. SOD、Vc和Zn对老年性白内障大鼠晶状体中Na-K ATP酶、Mg-ATP酶活性的影响[J]. 黑龙江医药科学, 2004, 27(2): 16-17 |
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| 作者姓名： | 杨笑天 邢进 张涤 |
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| 作者单位： | 佳木斯大学附属第一医院眼科,黑龙江,佳木斯,154002;佳木斯大学附属第一医院眼科,黑龙江,佳木斯,154002;佳木斯大学附属第一医院眼科,黑龙江,佳木斯,154002 |
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| 摘 要： | 目的 :旨在为防治大鼠半乳糖性白内障提供实验依据 ,进而为探索防治老年性白内障提供一定的理论依据。方法 :分别给予纯系 Wistar大鼠 4～ 5周龄腹腔注射 SOD,SOD和 Zn,SOD、 Zn和 Vc,共观察 2 0 d。结果 :SOD,SOD和 Zn,SOD、 Zn和 Vc联合用药均可使 Na- K ATP酶、Mg- ATP酶活性显著增高 (P <0 .0 1)。结论 :不同药物组对晶体混浊的抑制作用不同 ,联合用药组与单一用药组均对延缓晶体混浊效果最显著
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| 关 键 词： | SOD、Vc和Zn 白内障 Na-K ATP酶 Mg-ATP酶 |
| 文章编号： | 1008-0104(2004)02-0016-01 |
| 修稿时间： | 2004-03-04 |
Effect of SOD,Zn and Vc on Na-K ATPase, Mg-ATPase activity of lens in senile cataract rats |
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| YANG Xiao-tian,XING Jin,ZHANG Di. Effect of SOD,Zn and Vc on Na-K ATPase, Mg-ATPase activity of lens in senile cataract rats[J]. Heilongjiang Medicine and Pharmacy, 2004, 27(2): 16-17 |
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| Authors: | YANG Xiao-tian XING Jin ZHANG Di |
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| Abstract: | Objective: To provide the experimental evidence for the prevention and cure of galactose cataract in rats, adding the theoretical evidence to the prevention and cure of senile cataract. Methods:Wistar rats, aged 4~5weeks, were injected with SOD, SOD and Zn, SOD, Zn and Vc in the greater peritoneal cavity, respectively. All the rats were observed for 20 days. Results:Combined administration of SOD, SOD and Zn, SOD, Zn and Vc significantly increased Na-K ATPase and Mg-ATPase activities (P<0.01). Conclusions: Different drugs have different inhibitory effects on the crystal opacity. Both combined treatment and single treatment have the evident effect on the crystal opacity. |
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| Keywords: | SOD?Vc and Zn cataract Na-K ATPase Mg-ATPase |
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