| 组织工程化人工皮肤的超微结构研究 |
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| 引用本文： | 马刚,程滨珠,周余来,杨同书,颜炜群. 组织工程化人工皮肤的超微结构研究[J]. 中国麻风皮肤病杂志, 2005, 21(1): 4-6 |
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| 作者姓名： | 马刚 程滨珠 周余来 杨同书 颜炜群 |
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| 作者单位： | 1. 北京大学深圳医院,深圳,518036
2. 吉林大学再生医学研究所,长春,130021 |
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| 基金项目： | 卫生部立项课题，广东省医学科学基金课题 |
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| 摘 要： | 目的：观察组织工程化人工皮肤的超微结构特点。方法：制备组织工程化人工皮肤，超薄切片，透射电镜观察。结果：可见细胞间连接、张力细丝、透明角质颗粒和基底膜结构形成。结论：组织工程化人工皮肤在超微结构上与天然皮肤相近。
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| 关 键 词： | 组织工程化 人工皮肤 超微结构 基底膜 超薄切片 透射电镜观察 天然 细胞 透明 研究 |
| 修稿时间： | 2003-09-22 |
Ultrastructure research of the artificial skin with tissue- engineered composite |
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| Ma Gang,Cheng Binzhu,Zhou Yulai,et al.. Ultrastructure research of the artificial skin with tissue- engineered composite[J]. China Journal of Leprosy and Skin Diseases, 2005, 21(1): 4-6 |
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| Authors: | Ma Gang Cheng Binzhu Zhou Yulai et al. |
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| Affiliation: | Ma Gang,Cheng Binzhu,Zhou Yulai,et al. Department of Dermatology,Shenzhen Hospital,Beijing University,Shenzhen,518036 |
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| Abstract: | Objective: To study the ultrastructure of artificial skin with cultured composite. Methods: The artificial skin was reconstructed by planting fibroblasts and keratinocytes onto the collagen sponge separately, and then, was cultured for six weeks. The ultrastructure was observed under electronic microscopes. Results:The results showed that the connection between keratinocytes, tension filaments, keratohyaline granules and basilar membrane had been formed in the cultured composite artificial skin. Conclusion:The artificial skin with tissue-engineered composite has a similar ultrastructure to natural skin. |
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| Keywords: | artificial skin culture ultrastructure |
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