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阿托伐他汀对血脂正常1级或2级老年高血压的影响
引用本文:阮力,向群,闻维.阿托伐他汀对血脂正常1级或2级老年高血压的影响[J].现代医药卫生,2011,27(23):3543-3545.
作者姓名:阮力  向群  闻维
作者单位:怀化市第五人民医院,湖南怀化,418000
摘    要:目的:观察阿托伐他汀对血脂正常、1级或2级老年高血压的疗效.方法:本组52例随机分为治疗组27例和对照组25例,对照组给予左旋氨氯地平2.5 mg/次,每日上午1次,治疗组在上述基础上再予阿托伐他汀钙片10 mg/次,每日晚上1次,两组治疗共12周.结果:经治疗后4周、8周、12周,两组SBP 、DBP及PP均有所下降(P<0.01).治疗8周后,SBP、DBP及PP两组间差异均无统计学意义(P>0.05);治疗12周后,SBP、PP两组间差异均有统计学意义(P<0.05),但DBP改善情况两组差异无统计学意义.治疗前后血脂,无论组内或组间比较,差异均无统计学意义(P>0.05).结论:阿托伐他汀有一定协同降压作用,可促进选择性地降低SBP和缩小PP,有利于血脂正常、轻中度老年高血压的治疗.

关 键 词:阿托伐他汀  左旋氨氯地平  血脂正常  老年高血压  脉压

Effects of atorvastatin on mild-to-moderate senile hypertension with normal blood lipid
RUAN Li , XIANG Qun , WEN Wei.Effects of atorvastatin on mild-to-moderate senile hypertension with normal blood lipid[J].Modern Medicine Health,2011,27(23):3543-3545.
Authors:RUAN Li  XIANG Qun  WEN Wei
Institution:RUAN Li,XIANG Qun,WEN Wei(Department of Cardiology,Fifth People's Hospital of Huaihua City,Huaihua,Hunan 418000,China)
Abstract:Objective:To observe the effects of atorvastatin on mild-to-moderate senile hypertension with normal blood lipid.Methods:52 patients were randomly divided into the treatment group(n=27) and the control group(n=25).The control group was given levamlodipine 2.5mg once every morning for 12 week and the treatment group was given levamlodipine 2.5mg once every morning and atorvastatin calcium10mg once every night for 12 weeks.Results:After 4,8,12 weeks of treatment,SBP,DBP and PP were decreased in the two groups...
Keywords:Atorvastatin  Levamlodipine  Normal blood lipid  Snile hypertension  Pulse pressure  
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