红霉素针剂治疗儿童支原体肺炎中的临床观察

目的:观察红霉素针剂治疗儿童支原体肺炎的疗效及其不良反应.方法:将180例支原体肺炎患儿随机分成治疗组90例和对照组90例,治疗组使用红霉素针剂30 mg/(kg·d),对照组使用阿奇霉素针剂10 mg/(kg·d),观察两组用药5～7 d后的疗效及其不良反应.结果:治疗组显效率明显高于对照组,两组总有效率比较差异有统计学意义(P＜0.05).结论:红霉素治疗支原体肺炎显效率、安全性均高于阿奇霉素,值得儿科临床选用.

Clinical observation of erythrormycin injection in treatment of children mycoplasmal pneumonia

Objective：To study the effect and adverse reactions of erythromycin injection in treating children mycoplasmal pneumonia.Methods：180 children patients with mycoplasmal pneumonia were randomly divided into the therapy group（90 cases） and the control group（90 cases）.The therapy group was given erythromycin injection 30 mg/（kg·d） by intravenous drip for 5~7 d,while the control group was treated with azithromycin injection 10 mg/（kg·d） by intravenous drip for 5~7 d.The therapeutic effect and adverse reactions after 5~7 d of treatment were observed and compared between 2 groups.Results：The evident effective rate in the therapy group was significantly higher than that in the control group.The total effective rate had statistical difference between the two groups（P0.05）.Conclusion：The evident effective rate and safety of erythromycin are higher than those of azithromycin for treating mycoplasmal pneumonia.So erythromycin is worthy of being selected for application in clinical pediatrics.