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| 阿托伐他汀联合氯沙坦逆转改善原发性高血压左室肥厚的临床研究 | |
| 引用本文： | 马云海,姚成立,马云涛. 阿托伐他汀联合氯沙坦逆转改善原发性高血压左室肥厚的临床研究[J]. 现代医药卫生, 2011, 27(20): 3049-3050 |
| 作者姓名： | 马云海 姚成立 马云涛 |
| 作者单位： | 1. 宁夏医科大学,宁夏银川,750001 2. 银川市卫生局,宁夏银川,750001 3. 宁夏人民医院,宁夏银川,750001 |
| 摘 要： | 目的:观察阿托伐他汀联合氯沙坦治疗原发性高血压患者左室肥厚的效果.方法:选取原发性高血压左室肥厚患者84例,随机分为两组,阿托伐他汀和氯沙坦联合组43例,在基础治疗上加用阿托伐他汀20 mg,每日1次和氯沙坦50 ng,每日1次；氯沙坦组41例,在基础治疗上加用氯沙坦50 mg,每日1次,两组均治疗6个月,分析疗效.结果:联合治疗组舒张期室间隔厚度、舒张期左室后壁厚度、左室心肌重量指数治疗前后比较差异有统计学意义(P＜0.01),氯沙坦组舒张期室间隔厚度、舒张期左室后壁厚度、左室心肌重量指数治疗前后比较差异有统计学意义(P＜0.05),两组治疗后舒张期室间隔厚度、舒张期左室后壁厚度、左室心肌重量指数比较差异有统计学意义(P＜0.05).结论:阿托伐他丁联合氯沙坦治疗高血压,既可使血压、血脂迅速达标,又可有效逆转左室肥厚. |
| 关 键 词： | 左室肥厚 阿托伐他汀 氯沙坦 |
Clinical study of atorvastatin and losartan for improving left ventricular hypertrophy in patients with essential hypertension |
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| MA Yun-hai , YAO Cheng-li , MA Yun-tao. Clinical study of atorvastatin and losartan for improving left ventricular hypertrophy in patients with essential hypertension[J]. JOURNAL OF MODERN MEDICINE & HEALTH, 2011, 27(20): 3049-3050 | |
| Authors: | MA Yun-hai YAO Cheng-li MA Yun-tao |
| Affiliation: | 1.Ningxia Medical University,Yinchuan,Ningxia750001,China;2.Yinchuan Municipal Public Health Bureau,Yinchuan,Ningxia 750001, China ; 3.Ningxia People＇ s Hospital, Y inchuan , Ningxia750001, China) |
| Abstract: | Objective:To observe the treatment effect of atorvastatin and losartan on the essential hypertensive patients with left ventricular hypertrophy.Methods:84 cases of essential hypertensive patients with left ventricular hypertrophy(LUH) were randomly divided into two groups.On the base of basic treatment,the atorvastatin combined losartan group(n=43) was added atorvastatin 20mg and losartan 50mg,once daily,and the losartan group(n=41) was added losartan 50mg,once daily.Two groups were treated for 6 months.The... |
| Keywords: | Left ventricular hypertrophy Atorvastatin Losartan |
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