| 1988年上海地区甲型肝炎传播途径的探讨——120对配对病例对照研究 |
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| 引用本文： | 郭勤,胡善联,李永良,苏竹君,胡时豪,李申生.1988年上海地区甲型肝炎传播途径的探讨——120对配对病例对照研究[J].复旦学报(医学版),1988(5). |
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| 作者姓名： | 郭勤 胡善联 李永良 苏竹君 胡时豪 李申生 |
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| 作者单位： | 上海市徐汇区卫生防疫站
(郭勤，苏竹君，胡时豪)，上海医科大学公共卫生学院流行病学教研室
(胡善联，李永良)，上海市徐汇区卫生防疫站(李申生) |
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| 摘 要： | 120对1:2配对病例对照研究结果表明,1988年上海地区甲型肝炎暴发流行与接触肝炎患者、外出用餐、注射或输血、服用某些药物等传播途径无关,而与生食毛蚶有关(OR=23.20,X~2=69.22,p<0.0001),且罹患甲型肝炎的危险性OR值随生食毛蚶量上升(X_t~2=62.11,p<0.0001),控制年龄混杂因素后,仍有剂量反应关系。病例家属和(或)对照家属生食毛蚶者比未生食毛蚶者罹患甲型肝炎的危险性要高(OR=9.01,X~(MH)~2=29.97,p<0.0001)。
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| 关 键 词： | 毛蚶 甲型肝炎 传播途径 配对病例对照研究 |
THE TRANSMISSION OF HEPATITIS A IN SHANGHAI, 1988A OASE-OONTROL STUDY OF 120 MATCHED PAIRS |
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| Guo Qin,Hu Shanlian,Li Yongliang,Su Zhujun,Hu Shihao,Li Shensheng.THE TRANSMISSION OF HEPATITIS A IN SHANGHAI, 1988A OASE-OONTROL STUDY OF 120 MATCHED PAIRS[J].Fudan University Journal of Medical Sciences,1988(5). |
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| Authors: | Guo Qin Hu Shanlian Li Yongliang Su Zhujun Hu Shihao Li Shensheng |
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| Abstract: | A case-control study of 120 matched pairg (1:2) was carried out to study the transmission of an outbreak of hepatitis A in Shanghai, 1988. The results revealed that the transmission was mainly due to eating raw clams, Arca (Anadara) suberenata (OR = 23.20, x2 = 69.22, p<0.0001), but was not related to the other factors sach as contacting with hepatitis patients, eating out, injection or transfusion and taking medicine. Odds ratios of hepatitis A were increasing with the amounts of raw clams taken and Chi-square trend test was very significant (xt2 = 62.11, p<0,0001).Dose-response relationship still existed when the age factor was excluded.Case and/or control households taking raw clams had greater risk to acquire hepatitis A than those without (OR = 9.01, xMH2 = 29.97, p<0.0001). |
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| Keywords: | Arca(Anadara)suborenata hepatitis A transmission matched case-control study |
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